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冠状动脉搭桥术后短期再入住重症监护病房

Readmission To Intensive Care Unit After Coronary Bypass Operations in the Short Term.

作者信息

Gümüş Funda, Polat Adil, Yektaş Abdülkadir, Erentuğ Vedat, Alagöl Ayşin

机构信息

Department of Anaesthesia and Reanimation, Bağcılar Training and Research Hospital, İstanbul, Turkey.

Department of Cardiovascular Surgery, Bağcılar Training and Research Hospital, İstanbul, Turkey.

出版信息

Turk J Anaesthesiol Reanim. 2014 Aug;42(4):162-9. doi: 10.5152/TJAR.2014.99815. Epub 2014 May 29.

Abstract

OBJECTIVE

Intensive care unit (ICU) readmissions after coronary bypass (CABG) operations occur in a significant number of patients, and the prognosis is poor. We analyzed the risk factors for ICU readmissions after CABG operations.

METHODS

We retrospectively analyzed the prospectively collected data of 679 coronary bypass patients operated in a single institution in order to evaluate the risk factors for readmittance to the ICU with logistic regression analysis. The outcome results of patients readmitted to the ICU (Group R) and others (Group N) were compared.

RESULTS

Thirty-six (5.3%) patients were readmitted to the ICU. Postoperative in-hospital mortality and pulmonary and neurologic morbidity occurred in 43 (6.3%), 135 (19.9%), and 46 (6.8%) patients, respectively. The comparison of groups showed that mortality and morbidity were significantly higher in Group R compared to Group N (mortality 16.7% vs. 5.9, p=0.029; pulmonary morbidity 66.7% vs. 17.3%, p=0.0001; neurologic morbidity 38.9% vs. 5.0%, p=0.0001). Features associated with readmission included presence of left ventricular dysfunction preoperatively[odds ratio (OR)=4.1; 95% confidence interval (CI)=1.4-12.5; p=0.013], advanced NYHA Class (OR=5.3; 95% CI=1.3-21.7; p=0.022), pulmonary complications (OR=7.3; 95% CI=2.1-25.5; p=0.002), and neurologic complications (OR=4.6; 95% CI=1.3-16.7; p=0.021).

CONCLUSION

Patients readmitted to the ICU postoperatively have higher rates of mortality and pulmonary and neurologic morbidity after coronary bypass operations. Left ventricular dysfunction, advanced NYHA class, and postoperative pulmonary and neurologic complications are significant risk factors for readmission to the ICU.

摘要

目的

冠状动脉搭桥术(CABG)后重症监护病房(ICU)再入院情况在大量患者中出现,且预后较差。我们分析了CABG术后ICU再入院的危险因素。

方法

我们回顾性分析了在单一机构接受手术的679例冠状动脉搭桥患者的前瞻性收集数据,以便通过逻辑回归分析评估再次入住ICU的危险因素。比较了再次入住ICU的患者(R组)和其他患者(N组)的结果。

结果

36例(5.3%)患者再次入住ICU。术后院内死亡率、肺部和神经系统发病率分别发生在43例(6.3%)、135例(19.9%)和46例(6.8%)患者中。组间比较显示,R组的死亡率和发病率显著高于N组(死亡率16.7%对5.9%,p = 0.029;肺部发病率66.7%对17.3%,p = 0.0001;神经系统发病率38.9%对5.0%,p = 0.0001)。与再入院相关的特征包括术前存在左心室功能障碍[比值比(OR)= 4.1;95%置信区间(CI)= 1.4 - 12.5;p = 0.013]、纽约心脏协会(NYHA)分级较高(OR = 5.3;95% CI = 1.3 - 21.7;p = 0.022)、肺部并发症(OR = 7.3;95% CI = 2.1 - 25.5;p = 0.002)和神经系统并发症(OR = 4.6;95% CI = 1.3 - 16.7;p = 0.021)。

结论

术后再次入住ICU的患者在冠状动脉搭桥术后有更高的死亡率、肺部和神经系统发病率。左心室功能障碍、较高的NYHA分级以及术后肺部和神经系统并发症是再次入住ICU的重要危险因素。

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