Nibhoria Sarita, Kaur Tiwana Kanwardeep, Kaur Manmeet, Phutela Richa
Department of Pathology, Guru Gobind Singh Medical College AND Hospital, Faridkot, Punjab, India.
J Family Reprod Health. 2016 Mar;10(1):49-51.
Neurofibromas commonly involve peripheral nervous system. Isolated neurofibroma of vagina is very rare tumor and usually associated with Von Recklinghausen's disease. Vulva is the most frequent location of neurofibroma of genital tract followed by clitoris and labia. We present a rare case of neurofibroma of vaginal wall presented as vaginal cyst in a 52 year old female with no history of any other symptoms related to Recklinghausen's disease. Excision biopsy was done and on the histopathological examination non-encapsulated, well circumscribed mass composed of spindle shaped cells with wavy nuclei and bland nuclear chromatin was noted. Immunohistochemistry revealed strong positivity with S-100.
神经纤维瘤通常累及周围神经系统。孤立性阴道神经纤维瘤是一种非常罕见的肿瘤,通常与冯·雷克林豪森病相关。外阴是生殖道神经纤维瘤最常见的部位,其次是阴蒂和阴唇。我们报告一例罕见的阴道壁神经纤维瘤,表现为阴道囊肿,患者为一名52岁女性,无任何与雷克林豪森病相关的其他症状史。进行了切除活检,组织病理学检查发现一个无包膜、边界清楚的肿块,由核呈波浪状、核染色质平淡的梭形细胞组成。免疫组化显示S-100呈强阳性。