Hayashi K, Ohtsuki Y, Sonobe H, Hikita T, Iwata J, Furihata M, Mizobuchi T
2nd Dept. of Pathology, Kochi Medical School.
Gan No Rinsho. 1989 Jun;35(7):851-4.
A case of malignant transformation of a gastric hyperplastic polyp with a metaplastic bone formation is reported. A large gastric polyp was revealed by X-ray examination and by endoscopy in the cardia of a 89-year-old female who had complained of nausea. A polypectomy was performed since the biopsied materials had contained some atypical glands intermingled with hyperplastic glands. Histologically, the polyp, 1.7 x 1.0 x 0.6 cm in size, was a hyperplasic polyp that was found to contain superficial dysplastic foci associated with a moderately differentiated type of a tubular adenocarcinoma. A metaplasic bone formation was found in stroma beneath the hyperplastic glandular epithelium. Thus, polypectomy of hyperplastic polyps of the stomach of more than 1 cm with dysplastic foci is recommended.
报告了一例胃增生性息肉发生恶性转化并伴有化生骨形成的病例。一名89岁主诉恶心的女性，经X线检查和内镜检查发现贲门处有一个大的胃息肉。由于活检材料中含有一些与增生性腺体混合的非典型腺体，因此进行了息肉切除术。组织学检查显示，息肉大小为1.7×1.0×0.6 cm，是一个增生性息肉，发现其中含有与中分化管状腺癌相关的浅表发育异常灶。在增生性腺上皮下方的间质中发现了化生骨形成。因此，建议对直径超过1 cm且有发育异常灶的胃增生性息肉进行息肉切除术。
Zotero 插件