Xu Gui-Jun, Fu Xin, Tian Peng, Ma Jian-Xiong, Ma Xin-Long
Department of Orthopedics, Tianjin Hospital, Tianjin, 300211, People's Republic of China.
Biomechanics Labs of Orthopaedic Institute, Tianjin Hospital, No. 122 Munan Street, Hexi District, Tianjin, 300050, China.
J Orthop Surg Res. 2016 Jul 12;11(1):80. doi: 10.1186/s13018-016-0413-y.
The growing rod technique was applied in the treatment of early onset scoliosis (EOS) with promising outcomes and many complications at the same time. We reviewed data from literatures to compare the results of single growing rods with dual growing rods to achieve a clear understanding of this technique.
PubMed, Embase, MEDLINE, ScienceDirect, CNKI, Wanfang Data, and CQVIP were searched electronically until March 2016 using "growing rod" and "early onset scoliosis" as major search terms. Also, we manually searched other relevant conference proceedings. Two reviewers independently finished methodological quality assessment, data extraction, and calculations.
Six retrospective trials were adopted in data analysis including 126 and 119 patients in the single and dual rod groups, respectively. Significantly better coronal correction rates were observed immediately after the initial operation (MD = -14.67; 95 % CI -20.97 to -8.37; P < 0.01; I (2) = 0 %) and at the final follow-up (MD = -23.70; 95 % CI -45.87 to -1.52; P = 0.04; I (2) = 82 %) in the dual rod group. Similarly, better lengthening of the T1-S1 height occurred in the dual rod group immediately after the initial operation (MD = -1.74; 95 % CI -2.62 to -0.85; P < 0.01; I (2) = 0 %) and at final follow-up (MD = -3.8; 95 % CI -5.56 to -2.04; P < 0.001; I (2) = 36 %). There were more complications about the implant in the single rod group, while wound problems were common in the other group.
The data of the current meta-analysis showed advantages in the coronal correction rate and lengthening by dual growing rods with fewer implant-related complications and more wound complications.
生长棒技术已应用于早发性脊柱侧弯(EOS)的治疗,其疗效显著,但同时也伴随着许多并发症。我们回顾了文献数据,比较单根生长棒与双根生长棒的治疗结果,以更清楚地了解该技术。
以“生长棒”和“早发性脊柱侧弯”作为主要检索词,通过电子检索PubMed、Embase、MEDLINE、ScienceDirect、中国知网、万方数据和维普资讯,检索时间截至2016年3月。此外,我们还手动检索了其他相关会议论文集。两名研究者独立完成方法学质量评估、数据提取及计算。
数据分析纳入6项回顾性试验,单根生长棒组和双根生长棒组分别有126例和119例患者。双根生长棒组在初次手术后即刻(MD = -14.67;95%CI -20.97至-8.37;P < 0.01;I² = 0%)及末次随访时(MD = -23.70;95%CI -45.87至-1.52;P = 0.04;I² = 82%)的冠状面矫正率显著更高。同样,双根生长棒组在初次手术后即刻(MD = -1.74;95%CI -2.62至-0.85;P < 0.01;I² = 0%)及末次随访时(MD = -3.8;95%CI -5.56至-2.04;P < 0.001;I² = 36%)的T1-S1高度延长更明显。单根生长棒组植入物相关并发症更多,而另一组伤口问题较为常见。
当前荟萃分析的数据显示,双根生长棒在冠状面矫正率和延长方面具有优势,植入物相关并发症较少,但伤口并发症较多。