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确认鼻胃管放置位置:比色计与X射线的敏感度和特异性相同吗?一项诊断准确性研究。

Confirming nasogastric tube placement: Is the colorimeter as sensitive and specific as X-ray? A diagnostic accuracy study.

作者信息

Mordiffi Siti Zubaidah, Goh Mien Li, Phua Jason, Chan Yiong-Huak

机构信息

Evidence Based Nursing Unit, Nursing Department, National University Hospital, Singapore.

Evidence Based Nursing Unit, Nursing Department, National University Hospital, Singapore.

出版信息

Int J Nurs Stud. 2016 Sep;61:248-57. doi: 10.1016/j.ijnurstu.2016.06.011. Epub 2016 Jun 21.

Abstract

BACKGROUND

The effect of delivering enteral nutrition or medications via a nasogastric tube that is inadvertently located in the tracheobronchial tract can cause respiratory complications. Although radiographic examination is accepted as the gold standard for confirming the position of patients' enteral tubes, it is costly, involves risks of radiation, and is not failsafe. Studies using carbon dioxide sensors to detect inadvertent nasogastric tube placements have been conducted in intensive care settings. However, none involved patients in general wards.

OBJECTIVE

The objective of this study was to ascertain the diagnostic measure of colorimeter, with radiographic examination as the reference standard, to confirm the location of nasogastric tubes in patients.

DESIGN

A prospective observational study of a diagnostic test.

SETTING

This study was conducted in the general wards of an approximately 1100-bed acute care tertiary hospital of an Academic Medical Center in Singapore.

PARTICIPANTS

Adult patients with nasogastric tubes admitted to the general wards were recruited into the study.

METHODS

The colorimeter was attached to the nasogastric tube to detect for the presence of carbon dioxide, suggestive of a tracheobronchial placement. The exact location of the nasogastric tube was subsequently confirmed by a radiographic examination.

RESULTS

A total of 192 tests were undertaken. The colorimeter detected carbon dioxide in 29 tested nasogastric tubes, of which radiographic examination confirmed that four tubes were located in the tracheobronchial tract. The colorimeter failed to detect carbon dioxide in one nasogastric tube that was located in the tracheobronchial tract, thus, demonstrating a sensitivity of 0.80 [95% CI (0.376, 0.964)]. The colorimeter detected absence of carbon dioxide in 163 tested nasogastric tubes in which radiographic examination confirmed 160 gastrointestinal and one tracheobronchial placements, demonstrating a specificity of 0.865 [95% CI (0.808, 0.907)]. The colorimeter detected one tracheobronchial nasogastric tube placement that the radiographic examination was misinterpreted.

CONCLUSION

The study found that the use of the colorimeter in the general ward setting was not 100% sensitive or specific in ascertaining the location of a nasogastric tube as previously reported by many studies undertaken in intensive care settings. This is the first study on the use of a colorimeter to confirm the placement of a nasogastric tube in adult patients in the general ward setting. More research on the use of a colorimeter in the general ward setting and its potential use in certain processes for confirming the placement of a nasogastric tube is warranted.

摘要

背景

经意外置于气管支气管内的鼻胃管给予肠内营养或药物可导致呼吸系统并发症。尽管影像学检查被公认为确认患者肠内管位置的金标准,但它成本高、有辐射风险且并非万无一失。在重症监护环境中已开展了使用二氧化碳传感器检测鼻胃管意外置入情况的研究。然而,尚无涉及普通病房患者的研究。

目的

本研究的目的是以影像学检查为参考标准,确定比色计用于确认患者鼻胃管位置的诊断措施。

设计

一项关于诊断试验的前瞻性观察性研究。

地点

本研究在新加坡一所学术医疗中心的一家拥有约1100张床位的急性护理三级医院的普通病房进行。

参与者

纳入入住普通病房且留置鼻胃管的成年患者。

方法

将比色计连接到鼻胃管以检测是否存在二氧化碳,提示气管支气管置入。随后通过影像学检查确认鼻胃管的确切位置。

结果

共进行了192次检测。比色计在29根受试鼻胃管中检测到二氧化碳,其中影像学检查确认4根管子位于气管支气管内。比色计未能在1根位于气管支气管内的鼻胃管中检测到二氧化碳,因此,灵敏度为0.80 [95%置信区间(0.376, 0.964)]。比色计在163根受试鼻胃管中检测到无二氧化碳,其中影像学检查确认160根位于胃肠道,1根位于气管支气管,特异性为0.865 [95%置信区间(0.808, 0.907)]。比色计检测到1根气管支气管鼻胃管置入情况被影像学检查误判。

结论

该研究发现,在普通病房环境中使用比色计在确定鼻胃管位置方面并非如许多在重症监护环境中进行的研究所报道的那样具有100%的灵敏度或特异性。这是第一项关于在普通病房环境中使用比色计确认成年患者鼻胃管置入情况的研究。有必要对比色计在普通病房环境中的使用及其在确认鼻胃管置入的某些流程中的潜在用途进行更多研究。

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