White Michelle J, Duquette Debra, Bach Janice, Rafferty Ann P, Fussman Chris, Sharangpani Ruta, Russell Mark W
Department of Pediatrics and Communicable Diseases, Division of Pediatric Cardiology, University of Michigan, Ann Arbor, MI 48109, USA.
Genomics and Genetic Disorders Section, Michigan Department of Health and Human Services, Lansing, MI 48913, USA.
Healthcare (Basel). 2015 Nov 9;3(4):1086-96. doi: 10.3390/healthcare3041086.
Sudden cardiac death of the young (SCDY) is a devastating event for families and communities. Family history is a significant risk factor for this potentially preventable cause of death, however a complete and detailed family history is not commonly obtained during routine health maintenance visits. To estimate the proportion of adults with a family history of SCDY, the Michigan Department of Health and Human Services (MDHHS) Genomics Program included two questions within the 2007 Michigan Behavioral Risk Factor Survey (MiBRFS). Prevalence estimates and 95% confidence intervals were calculated. Among adults in Michigan, 6.3% reported a family history of SCDY, with a greater prevalence among blacks, those with lower household income, and those with less education. Among those reporting a family history of SCDY, 42.3% had at least one first-degree relative and 26.2% had multiple affected family members. This is the first study to demonstrate the prevalence of family history of SCDY while also highlighting key sociodemographic characteristics associated with increased prevalence. These findings should guide evidence-based interventions to reach those at greatest risk.
年轻人心脏性猝死(SCDY)对家庭和社区来说是一场毁灭性的事件。家族病史是这一潜在可预防死因的重要风险因素,然而在常规健康维护访视期间通常不会获取完整而详细的家族病史。为了估算有SCDY家族病史的成年人比例,密歇根州卫生与公众服务部(MDHHS)基因组学项目在2007年密歇根行为风险因素调查(MiBRFS)中纳入了两个问题。计算了患病率估计值和95%置信区间。在密歇根州的成年人中,6.3%报告有SCDY家族病史,黑人、家庭收入较低者以及受教育程度较低者的患病率更高。在报告有SCDY家族病史的人群中,42.3%至少有一名一级亲属,26.2%有多名受影响的家庭成员。这是第一项证明SCDY家族病史患病率,同时突出显示与患病率增加相关的关键社会人口学特征的研究。这些发现应指导基于证据的干预措施,以覆盖风险最大的人群。