Amodeo C, Perez J, Sturgill B C, Turner S M, Atuk N O
Department of Internal Medicine, University of Virginia Medical Center, Charlottesville 22908.
Arch Pathol Lab Med. 1989 Jul;113(7):800-2.
A 43-year-old white woman had a pheochromocytoma removed from her left adrenal gland, and one year later she developed a new left upper abdominal mass that was found to be a neuroblastoma. On both occasions, urinary vanillylmandelic acid level was elevated. However, urinary norepinephrine and epinephrine levels were increased only during the pheochromocytoma episode, while the urinary homovanillic acid level was elevated only when neuroblastoma developed. Despite a high suspicion of pheochromocytoma recurrence, the urinary catecholamine profile was suggestive of neuroblastoma, which was revealed by histopathologic analysis of the tumor tissue.
一名43岁的白人女性，其左侧肾上腺的嗜铬细胞瘤被切除，一年后她左中上腹出现了一个新肿块，经检查发现是神经母细胞瘤。在这两种情况下，尿香草扁桃酸水平均升高。然而，仅在嗜铬细胞瘤发作期间，尿去甲肾上腺素和肾上腺素水平升高，而仅在神经母细胞瘤发生时，尿高香草酸水平升高。尽管高度怀疑嗜铬细胞瘤复发，但尿儿茶酚胺谱提示为神经母细胞瘤，肿瘤组织的组织病理学分析证实了这一点。
