Brauer Fred
a Department of Mathematics , University of British Columbia , Vancouver , Canada.
J Biol Dyn. 2017 Aug;11(sup2):285-293. doi: 10.1080/17513758.2016.1207813. Epub 2016 Jul 19.
We consider an epidemic model in which all disease transmission is through shedding of virus by infectives and acquisition by susceptibles, rather than by direct contact. This leads to an susceptible-infectious-virus-removed (SIVR) model for which we can determine the basic reproduction number and the final size relation. We extend the model to an age of infection model with virus shedding a function of the age of infection.
我们考虑一种流行病模型,其中所有疾病传播都是通过感染者排出病毒并由易感者获取,而非通过直接接触。这导致了一个易感-感染-病毒-移除(SIVR)模型,我们可以据此确定基本再生数和最终规模关系。我们将该模型扩展为一个感染年龄模型,其中病毒排出是感染年龄的函数。