从脊柱到大脑进行原位神经调节的磁共振成像的技术挑战与安全性
Technical challenges and safety of magnetic resonance imaging with in situ neuromodulation from spine to brain.
作者信息
Thornton John S
机构信息
Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, UCLH NHS Foundation Trust, Queen Square, London, UK; Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, London, UK.
出版信息
Eur J Paediatr Neurol. 2017 Jan;21(1):232-241. doi: 10.1016/j.ejpn.2016.06.001. Epub 2016 Jun 20.
PURPOSE
This review summarises the need for MRI with in situ neuromodulation, the key safety challenges and how they may be mitigated, and surveys the current status of MRI safety for the main categories of neuro-stimulation device, including deep brain stimulation, vagus nerve stimulation, sacral neuromodulation, spinal cord stimulation systems, and cochlear implants.
REVIEW SUMMARY
When neuro-stimulator systems are introduced into the MRI environment a number of hazards arise with potential for patient harm, in particular the risk of thermal injury due to MRI-induced heating. For many devices however, safe MRI conditions can be determined, and MRI safely performed, albeit with possible compromise in anatomical coverage, image quality or extended acquisition time.
CONCLUSIONS
The increasing availability of devices conditional for 3 T MRI, whole-body transmit imaging, and imaging in the on-stimulation condition, will be of significant benefit to the growing population of patients benefitting from neuromodulation therapy, and open up new opportunities for functional imaging research.
目的
本综述总结了原位神经调节时进行磁共振成像（MRI）的必要性、关键安全挑战以及应对措施，并调查了主要类别神经刺激设备的MRI安全性现状，包括深部脑刺激、迷走神经刺激、骶神经调节、脊髓刺激系统和人工耳蜗。
综述总结
当神经刺激系统进入MRI环境时，会出现一些可能对患者造成伤害的风险，尤其是MRI诱导加热导致热损伤的风险。然而，对于许多设备而言，可以确定安全的MRI条件并安全地进行MRI检查，尽管可能在解剖覆盖范围、图像质量或延长采集时间方面有所妥协。
结论
适用于3T MRI、全身发射成像以及刺激状态下成像的设备越来越多，这将使越来越多受益于神经调节治疗的患者显著受益，并为功能成像研究开辟新的机会。
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