Bhatti Imran, Ojo Dotun, Dennison Ashley R, Rees Yvonne, Elabassy Mosheir, Garcea Giuseppe
Departments of *HPB Surgery †Radiology ‡Surgery, Leicester General Hospital, Leicester, UK.
Surg Laparosc Endosc Percutan Tech. 2016 Aug;26(4):334-7. doi: 10.1097/SLE.0000000000000288.
To determine the accuracy and safety of the percutaneous biopsy of pancreatic mass lesions.
Over a 12-year period clinical parameters, imaging, pathologic results, and complications were assessed in patients undergoing percutaneous biopsies pancreatic lesions.
One hundred fifty-three patients underwent pancreatic biopsy. The preferred modality for performing the biopsy was ultrasound (93%, n=143) followed by computerized tomography (7%, n=10). Histologic diagnosis was achieved in 147 patients, of which 3 (2%) were benign and 144 (94%) were malignant. Complications included a single death from overwhelming hemorrhage and 2 patients with morbidity (hematoma and cerebrovascular accident). The sensitivity and specificity of percutaneous biopsies was 90% and 95%, respectively.
Ultrasound-guided and computerized tomographic-guided percutaneous biopsy of pancreatic lesions is an effective and safe method to confirm or refute malignancy in suspicious pancreatic lesions. Endoscopic ultrasound-guided Tru-Cut may have the added advantage of avoiding the risk of peritoneal soiling.
确定胰腺肿块病变经皮活检的准确性和安全性。
在12年期间，对接受胰腺病变经皮活检的患者的临床参数、影像学、病理结果及并发症进行评估。
153例患者接受了胰腺活检。进行活检的首选方式是超声检查（93%，n = 143），其次是计算机断层扫描（7%，n = 10）。147例患者获得了组织学诊断，其中3例（2%）为良性，144例（94%）为恶性。并发症包括1例因大出血死亡和2例出现并发症（血肿和脑血管意外）。经皮活检的敏感性和特异性分别为90%和95%。
超声引导和计算机断层扫描引导下的胰腺病变经皮活检是确认或排除可疑胰腺病变恶性性质的有效且安全的方法。内镜超声引导下的Tru-Cut活检可能具有避免腹膜污染风险的额外优势。
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