Beniczky Sándor, Neufeld Miri, Diehl Beate, Dobesberger Judith, Trinka Eugen, Mameniskiene Ruta, Rheims Sylvain, Gil-Nagel Antonio, Craiu Dana, Pressler Ronit, Krysl David, Lebedinsky Angelina, Tassi Laura, Rubboli Guido, Ryvlin Philippe
Department of Clinical Neurophysiology, Danish Epilepsy Center, Dianalund, Denmark.
Aarhus University, Aarhus, Denmark.
Epilepsia. 2016 Sep;57(9):1363-8. doi: 10.1111/epi.13472. Epub 2016 Jul 21.
There is currently no international consensus procedure for performing comprehensive periictal testing of patients in the epilepsy monitoring units (EMUs). Our primary goal was to develop a standardized procedure for managing and testing patients during and after seizures in EMUs. The secondary goal was to assess whether it could be implemented in clinical practice (feasibility). A taskforce was appointed by the International League Against Epilepsy (ILAE)-Commission on European Affairs and the European Epilepsy Monitoring Unit Association, to develop a standardized ictal testing battery (ITB) based on expert opinion and experience with various local testing protocols. ITB contains a comprehensive set of 10 items that evidence the clinically relevant semiologic features, and it is adaptive to the dynamics of the individual seizures. The feasibility of the ITB was prospectively evaluated on 250 seizures from 152 consecutive patients in 10 centers. ITB was successfully implemented in clinical practice in all 10 participating centers and was considered feasible in 93% of the tested seizures. ITB was not feasible for testing seizures of very short duration.
目前,癫痫监测单元(EMU)中对患者进行全面发作期检测尚无国际共识程序。我们的主要目标是制定一套标准化程序,用于在EMU中对发作期间及发作后的患者进行管理和检测。次要目标是评估其能否在临床实践中实施(可行性)。国际抗癫痫联盟(ILAE)欧洲事务委员会和欧洲癫痫监测单元协会任命了一个特别工作组,根据专家意见和各种当地检测方案的经验,制定标准化发作期检测组合(ITB)。ITB包含一套全面的10项内容,可证明临床相关的发作症状学特征,并且能适应个体发作的动态变化。在10个中心对152例连续患者的250次发作前瞻性评估了ITB的可行性。ITB在所有10个参与中心均成功应用于临床实践,并且在93%的检测发作中被认为是可行的。ITB对于检测持续时间非常短的发作不可行。