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血清甘油三酯水平:急性胰腺炎并发症和结局的预测因素?

Serum Triglyceride Level: A Predictor of Complications and Outcomes in Acute Pancreatitis?

机构信息

Department of Medicine, Bronx-Lebanon Hospital Center, 1650 Selwyn Avenue, Suite No. 10C, Bronx, NY 10457, USA.

出版信息

Can J Gastroenterol Hepatol. 2016;2016:8198047. doi: 10.1155/2016/8198047. Epub 2016 Feb 25.

Abstract

Aim. To study serum triglyceride level as a predictor of complications and outcomes in acute pancreatitis. Methods. In this retrospective observational study, 582 patients admitted with acute pancreatitis, who had serum triglyceride levels measured within the first 24 hours, were divided into two groups. The study group consisted of patients with a triglyceride level ≥2.26 mmol/L (group 2) and the control group consisted of triglyceride level of <2.26 mmol/L (group 1). We collected data for baseline demographics, laboratory values, incidence of complications (local and systemic), admission to the intensive care unit (ICU), ICU length of stay, length of total hospital stay, and death in the two groups. Results. A triglyceride level of ≥2.26 mmol/L was found to be an independent predictor of developing altered mental status (p: 0.004), pancreatic necrosis (p: 0.001), acute respiratory distress syndrome (p: 0001), systemic Inflammatory response syndrome (p: 0.001), acute kidney injury (p: 0.001), hospital length of stay (LOS) (p: 0.002), admission to intensive care unit (ICU) (p: 0.002), and ICU LOS (p: 0.003). Conclusion. A triglyceride level of ≥2.26 mmol/L on admission in acute pancreatitis is an independent predictor of developing local and systemic complications, hospital LOS, admission to ICU, and ICU LOS.

摘要

目的

研究血清甘油三酯水平作为急性胰腺炎并发症和结局的预测因子。

方法

在这项回顾性观察性研究中,将 582 名在发病后 24 小时内测量血清甘油三酯水平的急性胰腺炎患者分为两组。研究组患者的甘油三酯水平≥2.26mmol/L(组 2),对照组患者的甘油三酯水平<2.26mmol/L(组 1)。我们收集了两组患者的基本人口统计学、实验室值、并发症(局部和全身)发生率、入住重症监护病房(ICU)、ICU 住院时间、总住院时间和死亡情况。

结果

发现甘油三酯水平≥2.26mmol/L是精神状态改变(p:0.004)、胰腺坏死(p:0.001)、急性呼吸窘迫综合征(p:0.001)、全身炎症反应综合征(p:0.001)、急性肾损伤(p:0.001)、住院时间(p:0.002)、入住 ICU(p:0.002)和 ICU 住院时间(p:0.003)的独立预测因子。

结论

急性胰腺炎患者入院时的甘油三酯水平≥2.26mmol/L是发生局部和全身并发症、住院时间、入住 ICU 和 ICU 住院时间的独立预测因子。

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