Lomas Derek J, Krambeck Amy E
Department of Urology, Mayo Clinic, Rochester, MN.
Department of Urology, Mayo Clinic, Rochester, MN.
Urology. 2016 Nov;97:208-211. doi: 10.1016/j.urology.2016.07.010. Epub 2016 Jul 19.
To evaluate long-term outcomes for men with benign prostatic obstruction (BPO) and concurrent detrusor underactivity (DUA) or acontractility following holmium laser enucleation of the prostate (HoLEP).
A retrospective chart review was performed on all patients with BPO and urodynamic evidence of DUA or acontractility secondary to a nonneurogenic etiology that underwent HoLEP at our institution over a 4-year period. Patients were included if they had at least 24 months of follow-up.
We identified 9 patients with DUA and 8 patients with acontractility who met inclusion criteria with median ages of 76 and 75 years, respectively. Preoperatively, 7 (77.8%) men with DUA and 8 (100%) men with acontractility had catheter-dependent urinary retention for a median of 2 and 5 months, respectively. Postoperatively, 8 (88.9%) men with DUA and 5 (62.5%) men with acontractility were catheter free, with a median follow-up of 50.9 and 38.6 months, respectively. All the men requiring catheterization were voiding spontaneously, but used intermittent catheterization for elevated postvoid residuals.
HoLEP appears to be an effective surgical option for patients with BPO and detrusor hypocontractility or acontractility, with durable results at follow-up greater than 24 months. However, patients with acontractile bladders should be counseled on possible need to for intermittent catheterization that may be needed for high postvoid residuals.
评估良性前列腺梗阻(BPO)合并逼尿肌活动低下(DUA)或无收缩力的男性患者在接受钬激光前列腺剜除术(HoLEP)后的长期疗效。
对我院4年内接受HoLEP治疗的所有BPO患者进行回顾性病历审查,这些患者有尿动力学证据表明DUA或无收缩力继发于非神经源性病因。如果患者至少有24个月的随访,则纳入研究。
我们确定了9例DUA患者和8例无收缩力患者符合纳入标准,中位年龄分别为76岁和75岁。术前,7例(77.8%)DUA男性患者和8例(100%)无收缩力男性患者依赖导尿管排尿,中位时间分别为2个月和5个月。术后,8例(88.9%)DUA男性患者和5例(62.5%)无收缩力男性患者无需导尿管,中位随访时间分别为50.9个月和38.6个月。所有需要导尿的男性患者均能自主排尿,但因残余尿量增加而使用间歇性导尿。
HoLEP似乎是BPO合并逼尿肌收缩力减弱或无收缩力患者的一种有效手术选择,随访24个月以上效果持久。然而,对于膀胱无收缩力的患者,应告知其可能需要间歇性导尿以处理高残余尿量。