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加拿大光源中心的BMIT设施:X射线相敏成像技术进展

BMIT facility at the Canadian Light Source: Advances in X-ray phase-sensitive imaging.

作者信息

Wysokinski T W, Ianowski J P, Luan X, Belev G, Miller D, Webb M A, Zhu N, Chapman D

机构信息

Canadian Light Source, Saskatoon, SK, Canada.

Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK, Canada.

出版信息

Phys Med. 2016 Dec;32(12):1753-1758. doi: 10.1016/j.ejmp.2016.07.090. Epub 2016 Jul 21.

DOI:10.1016/j.ejmp.2016.07.090
PMID:27453203
Abstract

The BioMedical Imaging and Therapy (BMIT) facility [1,2] located at the Canadian Light Source, provides synchrotron-specific imaging and radiation therapy capabilities. There are two separate beamlines used for experiments: the bending magnet (05B1-1) and the insertion device (05ID-2) beamline. The bending magnet beamline provides access to monochromatic beam spanning a spectral range of 15-40keV, and the beam is 240mm wide in the POE-2 experimental hutch. Users can also perform experiments with polychromatic (pink) beam. The insertion device beamline was officially opened for general user program in 2015. The source for the ID beamline is a multi-pole, superconducting 4.3T wiggler. The high field gives a critical energy over 20keV. The optics hutches prepare a beam that is 220mm wide in the last experimental hutch SOE-1. The monochromatic spectral range spans 25-150+keV. Several different X-ray detectors are available for both beamlines, with resolutions ranging from 2μm to 200μm. BMIT provides a number of imaging techniques including standard absorption X-ray imaging, K-edge subtraction imaging (KES), in-line phase contrast imaging (also known as propagation based imaging, PBI) and Diffraction Enhanced Imaging/Analyzer Based Imaging (DEI/ABI), all in either projection or CT mode. PBI and DEI/ABI are particularly important tools for BMIT users since these techniques enable visualization of soft tissue and allow for low dose imaging.

摘要

位于加拿大光源中心的生物医学成像与治疗(BMIT)设施[1,2],具备同步加速器特有的成像和放射治疗能力。有两条独立的光束线用于实验:弯转磁铁(05B1-1)光束线和插入件(05ID-2)光束线。弯转磁铁光束线可提供能量范围为15 - 40keV的单色光束,在POE-2实验小屋中光束宽度为240mm。用户也可以使用多色(粉色)光束进行实验。插入件光束线于2015年正式向普通用户开放。该插入件光束线的光源是一个多极超导4.3T摆动器。高场使得临界能量超过20keV。光学小屋在最后一个实验小屋SOE-1中准备出宽度为220mm的光束。单色光谱范围为25 - 150 + keV。两条光束线都有几种不同的X射线探测器可供使用,分辨率范围从2μm到200μm。BMIT提供多种成像技术,包括标准吸收X射线成像、K边减影成像(KES)、在线相衬成像(也称为基于传播的成像,PBI)以及衍射增强成像/基于分析仪的成像(DEI/ABI),所有这些技术都可在投影或CT模式下进行。PBI和DEI/ABI对BMIT用户来说是特别重要的工具,因为这些技术能够实现软组织可视化并允许低剂量成像。

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