Freis A, Elsässer M, Sohn C, Fluhr H
Gynecological endocrinology and fertility disorders, University Hospital Heidelberg, Heidelberg, Germany.
Gynecology and Obstetrics, University Hospital Heidelberg, Heidelberg, Germany.
Geburtshilfe Frauenheilkd. 2016 Jul;76(7):819-822. doi: 10.1055/s-0042-109398.
Twin pregnancy consisting of one fetus and one complete mole (CMCF, complete hydatidiform mole and a coexistent fetus) is an obstetric rarity with an incidence of 1/22 000 to 1/100 000 pregnancies. Associated risks include prematurity, intrauterine death, vaginal bleeding, preeclampsia, hyperthyroidism, theca lutein cysts, uterine rupture and the development of malignant neoplasia in the form of a trophoblastic tumour (GTD, persistent gestational trophoblastic disease), which is thought to be the most common complication. We report the case of a 33-year-old patient diagnosed with CMCF in the 15th week of pregnancy. After comprehensive counselling the patient chose to proceed with her pregnancy under close observation and prophylactic fetal lung maturation. We were able to extend the pregnancy to 32 weeks gestation when heavy vaginal bleeding forced a decision to deliver by caesarean section.
双胎妊娠中一个为胎儿，另一个为完全性葡萄胎（CMCF，即完全性葡萄胎合并共存胎儿）是一种产科罕见情况，在妊娠中的发生率为1/22000至1/100000。相关风险包括早产、宫内死亡、阴道出血、子痫前期、甲状腺功能亢进、黄素囊肿、子宫破裂以及滋养细胞肿瘤形式的恶性肿瘤（GTD，持续性妊娠滋养细胞疾病）的发生，后者被认为是最常见的并发症。我们报告一例33岁患者，在妊娠第15周被诊断为CMCF。经过全面咨询，患者选择在密切观察和预防性胎儿肺成熟的情况下继续妊娠。当严重阴道出血迫使我们决定行剖宫产分娩时，我们成功将妊娠延长至妊娠32周。
