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2008 - 2012年俄亥俄陆军国民警卫队成员代表性样本中情绪和焦虑障碍的发病率及风险

Incidence and Risk for Mood and Anxiety Disorders in a Representative Sample of Ohio Army National Guard Members, 2008-2012.

作者信息

Fink David S, Chen Qixuan, Liu Yutao, Tamburrino Marijo B, Liberzon Israel, Shirley Edwin, Fine Thomas, Cohen Gregory H, Galea Sandro, Calabrese Joseph R

机构信息

Columbia University, Mailman School of Public Health, Department of Epidemiology, New York, NY.

Columbia University, Mailman School of Public Health, Department of Biostatistics, New York, NY.

出版信息

Public Health Rep. 2016 Jul-Aug;131(4):614-22. doi: 10.1177/0033354916662221.

Abstract

OBJECTIVE

We investigated the incidence of first-onset psychiatric disorders among Ohio Army National Guard members and the sociodemographic and military factors associated with these incident disorders. We aimed to identify potential risk factors and mitigating factors for a range of psychiatric disorders in a representative military sample.

METHODS

We analyzed data on a representative sample of 528 Ohio Army National Guard members who were assessed in person annually for first-onset psychiatric disorders from 2008 through 2012 using structured clinical interviews. We used a multivariable discrete-time Cox proportional hazard model to determine risk factors of first-onset anxiety or mood disorders.

RESULTS

The annualized incidence rate of any first-onset psychiatric disorder was 9.8 per 100 person-years at risk. Alcohol use disorder and major depressive disorder had the highest incidence rates among the unique disorders under study (5.0 and 4.2 per 100 person-years at risk, respectively). We found an association between respondents endorsing past-year deployment and a 29% increase in the risk of incident anxiety or mood disorder, whereas the past-year experience of any non-deployment traumatic event was associated with a 32% increase in risk of incident anxiety or mood disorder.

CONCLUSION

Soldiers experience a substantial burden of first-onset alcohol use disorder and major depressive disorder annually; the experience of non-deployment-related traumatic events contributes substantially to increasing risk, suggesting that any effort aimed at mitigating mood and anxiety disorders in this population must consider the soldier's life experience and military experience.

摘要

目的

我们调查了俄亥俄陆军国民警卫队成员中首次发作的精神障碍的发病率,以及与这些新发疾病相关的社会人口学和军事因素。我们旨在确定具有代表性的军事样本中一系列精神障碍的潜在风险因素和缓解因素。

方法

我们分析了528名俄亥俄陆军国民警卫队成员的代表性样本数据,这些成员在2008年至2012年期间每年接受针对首次发作精神障碍的结构化临床访谈评估。我们使用多变量离散时间Cox比例风险模型来确定首次发作焦虑或情绪障碍的风险因素。

结果

任何首次发作精神障碍的年化发病率为每100人年9.8例。在研究的单一疾病中,酒精使用障碍和重度抑郁症的发病率最高(分别为每100人年5.0例和4.2例)。我们发现,报告过去一年有部署经历的受访者发生焦虑或情绪障碍的风险增加29%,而过去一年经历任何非部署创伤事件与发生焦虑或情绪障碍的风险增加32%相关。

结论

士兵每年经历首次发作酒精使用障碍和重度抑郁症的沉重负担;非部署相关创伤事件的经历极大地增加了风险,这表明任何旨在减轻该人群情绪和焦虑障碍的努力都必须考虑士兵的生活经历和军事经历。

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