Kaczmarek Maria, Trambacz-Oleszak Sylwia
Department of Human Biological Development, Institute of Anthropology, Faculty of Biology, Adam Mickiewicz University, Poznań, Umultowska 89, 61-614, Poznan, Poland.
Qual Life Res. 2017 Jan;26(1):95-106. doi: 10.1007/s11136-016-1371-x. Epub 2016 Jul 27.
To evaluate the relationship between recent stressful life events (SLEs), stress-related symptoms (SRSs), and health-related quality of life (HRQoL) in children beginning primary school.
A community-based sample of 6- to 8-year-old children (176 boys and 175 girls at baseline) participated in a prospective longitudinal study with three waves of data collection and 1-year interval between subsequent surveys, conducted in the Wielkopolska Province, Poland. Main exposures included nine recent stressful life events and psychosomatic and behavioural symptoms related to stress (SRSs), both self-reported by children. The outcome was total HRQoL assessed by a Polish version of the PedsQL™ 4.0 (Pediatric Quality of Life Inventory) Generic Core Scales questionnaire, 5- to 7-year-old version. To evaluate the relationship between total HRQoL and predictor variables, a latent growth curve (LGC) model using multiple group design (boys and girls) with three waves and two time-varying covariates, the SLEs and SRSs, was applied.
An unconditional multi-group LGC model revealed that the total HRQoL changed over time in a linear trajectory. After incorporating to the model, two time-varying covariates, SLEs and SRSs, the first predictor for HRQoL was only significant at the last wave in girls and at two subsequent waves, except for baseline, in boys. The second predictor revealed significant negative impacts on HRQoL over the entire period of time in both boys and girls suggesting that the pathway underlying the association of SLEs with HRQoL may be mediated by SRSs. Mean values of HRQoL at each time points did not show gender differences.
The findings of the present study may help to develop and implement a health and safety protection training programmes addressed to parents, caregivers, and practitioners to make children's lives easier.
评估刚上小学的儿童近期应激性生活事件（SLEs）、应激相关症状（SRSs）与健康相关生活质量（HRQoL）之间的关系。
在波兰大波兰省进行了一项基于社区的研究，样本为6至8岁儿童（基线时176名男孩和175名女孩），参与一项前瞻性纵向研究，进行三轮数据收集，后续调查间隔为1年。主要暴露因素包括儿童自我报告的9项近期应激性生活事件以及与应激相关的身心和行为症状（SRSs）。结局指标是通过波兰版PedsQL™ 4.0（儿童生活质量量表）通用核心量表问卷5至7岁版本评估的总体HRQoL。为了评估总体HRQoL与预测变量之间的关系，应用了具有三组设计（男孩和女孩）、三轮数据以及两个随时间变化的协变量（SLEs和SRSs）的潜在增长曲线（LGC）模型。
无条件多组LGC模型显示，总体HRQoL随时间呈线性轨迹变化。在模型中纳入两个随时间变化的协变量SLEs和SRSs后，HRQoL的第一个预测因素仅在女孩的最后一轮以及男孩除基线外的随后两轮中具有显著性。第二个预测因素在男孩和女孩的整个时间段内均显示出对HRQoL有显著负面影响，这表明SLEs与HRQoL关联的潜在途径可能由SRSs介导。每个时间点的HRQoL平均值未显示出性别差异。
本研究结果可能有助于制定和实施针对家长、照顾者和从业者的健康与安全保护培训计划，以使儿童的生活更轻松。
