Athanasopoulos Leonidas V, Moscarelli Marco, Speziale Giuseppe, Punjabi Prakash P, Athanasiou Thanos
1 Department of Cardiothoracic Surgery, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK.
2 Cardiac Surgery Department, Anthea Hospital, GVM Hospitals of Care and Research, Bari, Italy.
Perfusion. 2017 Mar;32(2):92-96. doi: 10.1177/0267659116662520. Epub 2016 Jul 28.
This review focused on whether subvalvular techniques are more effective than isolated restrictive annuloplasty in addressing ischemic mitral regurgitation (MR). Searching identified 445 papers and, following a selection process, we ended up with 10 articles. Two were propensity-matched studies, four retrospective and four prospective, non-randomized studies. The end points of interest were late recurrence of MR, other early echocardiographic outcomes of mitral function and early mortality. All studies focusing on echocardiographic measurements showed improved results in the groups where subvalvular repair techniques were used. In almost all studies, the recurrence of MR postoperatively was less when subvalvular techniques were used. No difference in early or in-hospital mortality was demonstrated in all four studies that included comparisons. We conclude that subvalvular techniques in combination with annuloplasty are safe and may better address ischemic MR than the use of annuloplasty ring alone.
本综述聚焦于在治疗缺血性二尖瓣反流(MR)方面,瓣下技术是否比单纯限制性瓣环成形术更有效。通过检索识别出445篇论文,经过筛选过程,最终得到10篇文章。其中2篇为倾向匹配研究,4篇为回顾性研究,4篇为前瞻性、非随机研究。关注的终点为MR的晚期复发、二尖瓣功能的其他早期超声心动图结果以及早期死亡率。所有聚焦于超声心动图测量的研究均显示,使用瓣下修复技术的组结果有所改善。在几乎所有研究中,使用瓣下技术时术后MR的复发较少。在纳入比较的所有四项研究中,未显示早期或院内死亡率存在差异。我们得出结论,瓣下技术联合瓣环成形术是安全的,并且与单独使用瓣环成形环相比,可能能更好地治疗缺血性MR。