Juneau Daniel, Erthal Fernanda, Chow Benjamin J W, Redpath Calum, Ruddy Terrence D, Knuuti Juhani, Beanlands Rob S
National Cardiac PET Centre, Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.
Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada.
J Nucl Cardiol. 2016 Dec;23(6):1380-1398. doi: 10.1007/s12350-016-0599-8. Epub 2016 Jul 28.
Sudden cardiac death (SCD) represents a significant portion of all cardiac deaths. Current guidelines focus mainly on left ventricular ejection fraction (LVEF) as the main criterion for SCD risk stratification and management. However, LVEF alone lacks both sensitivity and specificity in stratifying patients. Recent research has provided interesting data which supports a greater role for advanced cardiac imaging in risk stratification and patient management. In this article, we will focus on nuclear cardiac imaging, including left ventricular function assessment, myocardial perfusion imaging, myocardial blood flow quantification, metabolic imaging, and neurohormonal imaging. We will discuss how these can be used to better understand SCD and better stratify patient with both ischemic and non-ischemic cardiomyopathy.
心脏性猝死（SCD）占所有心脏性死亡的很大一部分。当前指南主要将左心室射血分数（LVEF）作为SCD风险分层和管理的主要标准。然而，仅LVEF在对患者进行分层时缺乏敏感性和特异性。最近的研究提供了有趣的数据，支持先进的心脏成像在风险分层和患者管理中发挥更大作用。在本文中，我们将重点关注核心脏成像，包括左心室功能评估、心肌灌注成像、心肌血流定量、代谢成像和神经激素成像。我们将讨论如何利用这些成像更好地理解SCD，并对缺血性和非缺血性心肌病患者进行更好的分层。
