Dahl John P, Purcell Patricia L, Parikh Sanjay R, Inglis Andrew F
Department of Otolaryngology-Head & Neck Surgery, University of Washington, Seattle Children's Hospital, Seattle, Washington, U.S.A.
Department of Otolaryngology-Head & Neck Surgery, Indiana University School of Medicine, Indianapolis, Indiana, U.S.A.
Laryngoscope. 2017 Jan;127(1):252-257. doi: 10.1002/lary.26200. Epub 2016 Jul 28.
To evaluate outcomes of the endoscopic posterior cricoid split with rib graft (EPCS/RG) procedure in the treatment of subglottic stenosis (SGS), posterior glottic stenosis (PGS), and bilateral vocal fold immobility (BVFI).
Retrospective chart review.
Chart review of all patients who underwent EPCS/RG at a single tertiary-care facility between 1999 and 2014. Patients were grouped based on the primary indication for the procedure. Decannulation was the primary endpoint. Secondary endpoints were the number of subsequent airway procedures and length of hospitalization.
Thirty-three patients were identified; 32 had tracheotomy. Overall decannulation rate was 65.6%. Subgroup analysis demonstrated the following decannulation rates: 53.8% for SGS, 100% for PGS, and 28.6% for BVFI. Fisher exact test found a significant difference in overall decannulation rates between groups (P = 0.002). Operation-specific decannulation rates for patients who never required an open procedure were 23% for SGS, 91.6% for PGS, and 28.6% for BVFI. This difference was also statistically significant (P = 0.001). Multivariate logistic regression analysis found prematurity had a positive correlation with decannulation that approached statistical significance (P < 0.051; odds ratio 6.1; 95% confidence interval 0.99, 37.6). The percentage of patients who underwent repeat airway procedures for the groups was 61.5% for SGS, 16.6 % for PGS, and 14.3% for BVFI. The median length of hospitalization after EPCS/RG was 3 days.
This represents the largest series of patients who have undergone EPCS/RG and demonstrates that the majority of patients can be decannulated after this procedure. Patients with PGS had the highest operation-specific decannulation rates.
评估内镜下环状软骨后裂开联合肋软骨移植术(EPCS/RG)治疗声门下狭窄(SGS)、声门后狭窄(PGS)及双侧声带麻痹(BVFI)的疗效。
回顾性病历分析。
回顾1999年至2014年间在一家三级医疗中心接受EPCS/RG手术的所有患者的病历。根据手术的主要适应证对患者进行分组。拔管是主要终点。次要终点是后续气道手术的次数和住院时间。
共纳入33例患者;32例行气管切开术。总体拔管率为65.6%。亚组分析显示以下拔管率:SGS为53.8%,PGS为100%,BVFI为28.6%。Fisher精确检验发现各组总体拔管率存在显著差异(P = 0.002)。从未需要开放手术的患者的手术特异性拔管率:SGS为23%,PGS为91.6%,BVFI为28.6%。这种差异也具有统计学意义(P = 0.001)。多因素逻辑回归分析发现早产与拔管呈正相关,接近统计学意义(P < 0.051;比值比6.1;95%置信区间0.99,37.6)。各组接受重复气道手术的患者百分比:SGS为61.5%,PGS为16.6%,BVFI为14.3%。EPCS/RG术后的中位住院时间为3天。
这是接受EPCS/RG手术患者数量最多的系列研究,表明大多数患者在此手术后可以拔管。PGS患者的手术特异性拔管率最高。
4。《喉镜》,2017年,第127卷,第252 - 257页