肝胰联合切除术的结果与并发症：一项回顾性分析。

Outcome and complications of combined liver and pancreas resections: a retrospective analysis.

作者信息

Benzing Christian, Hau Hans-Michael, Atanasov Georgi, Broschewitz Johannes, Krenzien Felix, Bartels Michael, Wiltberger Georg

机构信息

a Department of Visceral, Transplantation, Vascular and Thoracic Surgery , University Hospital of Leipzig , Leipzig , Germany.

出版信息

Acta Chir Belg. 2016 Dec;116(6):340-345. doi: 10.1080/00015458.2016.1186962. Epub 2016 Jul 29.

DOI:10.1080/00015458.2016.1186962

PMID:27471834

Abstract

BACKGROUND

Combined resections of the liver and pancreas are related to high complication and mortality rates. The present study assessed the outcome of these procedures and identified specific risk factors for morbidity and mortality.

METHODS

Between January 2001 and April 2012, 28 combined liver/pancreas resections were performed at our institution. All patients were retrospectively analysed using a database with regards to baseline characteristics, surgical procedures, complications and survival.

RESULTS

Among the pancreatic resections, there were 12 (42.9%) Kausch-Whipple (KW), 9 (32.1%) pylorus-preserving pancreaticoduodenectomy (PPPD), 6 (21.4%) distal pancreatectomies (DP) and 1 (3.6%) total pancreaticoduodenectomy (TPD). In 12 (48.9%) cases, major complications (grade IIIb-V) were observed. Overall survival was 35 months (SD = 40.5) and the 3-year survival rate was 35.7% (1-year survival rate: 50%).

DISCUSSION

Combined resections of the liver and pancreas are associated with high complication rates, especially if major liver resections are performed. Therefore, it is mandatory to do a thorough evaluation of potential patients.

摘要

背景

肝脏和胰腺联合切除术与高并发症及死亡率相关。本研究评估了这些手术的结果，并确定了发病和死亡的特定风险因素。

方法

2001年1月至2012年4月期间，我们机构进行了28例肝脏/胰腺联合切除术。使用数据库对所有患者的基线特征、手术过程、并发症和生存率进行回顾性分析。

结果

在胰腺切除术中，有12例（42.9%）考施-惠普尔（KW）手术、9例（32.1%）保留幽门的胰十二指肠切除术（PPPD）、6例（21.4%）胰体尾切除术（DP）和1例（3.6%）全胰十二指肠切除术（TPD）。12例（48.9%）患者出现严重并发症（Ⅲb-V级）。总生存期为35个月（标准差=40.5），3年生存率为35.7%（1年生存率：50%）。