Department of Nuclear Physics, Sub-nuclear and Radiation, Guglielmo Marconi University, Rome, Italy.
2nd Medical Faculty, Charles University, Bulovka Hospital, Institute of Clinical and Experimental Medicine, Prague, Czech Republic.
J Biol Regul Homeost Agents. 2016 Apr-Jun;30(2 Suppl 3):29-34.
Psoriasis is generally considered as an autoimmune inflammatory cutaneous-systemic disease, with chronic course and high rate of recurrence, while its high risk of comorbidities affect the patients quality of life significantly. Despite the good therapeutic response, most of the available options show tendency for poor tolerance and high rate of occurrence of side effects. Therefore, the interest of patients and doctors to investigate the possibility of treating psoriasis with natural substances is not surprising. The aim of this study was to investigate the efficacy and safety of the herbal skin-care product Dr Michaels® (Soratinex®) for the management of chronic plaque psoriasis, within a 6 to 8 week treatment course. Thirty patients of both sexes, aged between 24 and 70 years with mild to moderate psoriasis vulgaris were included in this study. The products of Dr Michaels® (Soratinex®) were applied in sequence: cleansing gel, ointment after 3-4 minutes and tonic care (for the fire-smeared ointment) 2 times per day for restorative care and cleansing gel for psoriasis within scalp 3 times a week. The study lasted six weeks. The severity and extent of the lesions were evaluated by PASI score (Psoriasis Area and Severity Index). Based on the obtained result, the products of Dr Michaels® (Soratinex®) have proved to be effective in the treatment of mild and moderate psoriasis vulgaris. In the study group, no improvement was observed in 10% of patients, a slight improvement in 20%, good in 40% and very good in 16.6% of patients.
银屑病通常被认为是一种自身免疫性炎症性皮肤-系统性疾病,具有慢性病程和高复发率,而其高合并症风险显著影响患者的生活质量。尽管治疗效果良好,但大多数可用的治疗方案显示出耐受性差和副作用发生率高的趋势。因此,患者和医生对用天然物质治疗银屑病的可能性产生兴趣并不奇怪。本研究旨在探讨 Dr Michaels®(Soratinex®)草药护肤品在 6-8 周治疗过程中治疗慢性斑块型银屑病的疗效和安全性。本研究纳入了 30 名年龄在 24 至 70 岁之间的男女患者,患有轻度至中度寻常型银屑病。Dr Michaels®(Soratinex®)的产品按以下顺序使用:清洁凝胶、3-4 分钟后使用软膏,每日两次使用爽肤滋润剂(针对火灼软膏)进行修复护理,每日清洁头皮上的银屑病 3 次。研究持续 6 周。通过 PASI 评分(银屑病面积和严重程度指数)评估病变的严重程度和范围。根据获得的结果,“Dr Michaels®(Soratinex®)”产品已被证明对轻度和中度寻常型银屑病的治疗有效。在研究组中,10%的患者无改善,20%的患者稍有改善,40%的患者改善良好,16.6%的患者非常好。