具有印戒细胞特征的CD30+原发性皮肤移植后淋巴组织增生性疾病
CD30+ Primary Cutaneous Post-transplant Lymphoproliferative Disorder with Signet-ring Cell Features.
作者信息
Malviya Neeta, Wickless Heather
机构信息
Department of Dermatology, University of Texas Southwestern Medical Center , Dallas, TX, USA.
出版信息
Hematol Rep. 2016 Jun 27;8(2):6433. doi: 10.4081/hr.2016.6433. eCollection 2016 May 10.
Abstract
We report a case of primary cutaneous CD30+ post-transplant lymphoproliferative disorder with an uncommon finding of signet ring cell features in a heart transplant patient. The neoplastic cells were CD4 and CD30 positive, and negative for S-100, pancytokeratin, myeloperoxidase, and CD56. In situ hybridization for Epstein Barr Virus (EBV) was negative, even though the patient did have EBV viremia.
摘要
我们报告了一例心脏移植患者的原发性皮肤CD30+移植后淋巴组织增生性疾病，其具有罕见的印戒细胞特征。肿瘤细胞CD4和CD30呈阳性，而S-100、全细胞角蛋白、髓过氧化物酶和CD56呈阴性。尽管该患者确实存在EBV病毒血症，但爱泼斯坦-巴尔病毒（EBV）原位杂交结果为阴性。
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