阿莫西林/克拉维酸（奥格门汀）引起的肝内胆汁淤积。
Amoxycillin/clavulanic acid (Augmentin)-induced intrahepatic cholestasis.
作者信息
Dowsett J F, Gillow T, Heagerty A, Radcliffe M, Toadi R, Isle I, Russell R C
机构信息
Department of Gastroenterology, University College and Middlesex Hospital, Medical School, U.K.
出版信息
Dig Dis Sci. 1989 Aug;34(8):1290-3. doi: 10.1007/BF01537281.
PMID:2752877
Abstract
A 75-year-old man developed a biopsy-proven, drug-induced intrahepatic cholestasis after use of amoxycillin trihydrate combined with the beta-lactam inhibitor potassium clavulanate (Augmentin). Cholestatic liver injury is an uncommonly recognized, probably immunologically based adverse reaction to therapy with penicillin and its derivatives.
摘要
一名75岁男性在使用三水阿莫西林联合β-内酰胺酶抑制剂克拉维酸钾（阿莫西林克拉维酸钾）后，经活检证实发生了药物性肝内胆汁淤积。胆汁淤积性肝损伤是一种对青霉素及其衍生物治疗罕见的、可能基于免疫的不良反应。
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