Baldasseroni Samuele, Pratesi Alessandra, Francini Sara, Pallante Rachele, Barucci Riccardo, Orso Francesco, Burgisser Costanza, Marchionni Niccolò, Fattirolli Francesco
Department of Experimental and Clinical Medicine, University of Florence and Azienda Ospedaliero Universitaria Careggi, Florence, Italy.
J Am Geriatr Soc. 2016 Aug;64(8):1640-5. doi: 10.1111/jgs.14239.
To assess the effect of cardiac rehabilitation (CR) and identify predictors of changes in functional capacity with CR in a consecutive series of older adults with a recent cardiac event.
Observational.
In-hospital CR unit.
Individuals aged 75 and older referred to an outpatient CR Unit after an acute coronary event (unstable angina pectoris, acute myocardial infarction) or cardiac surgery (coronary artery bypass grafting, heart valve replacement or repair) (N = 160, mean age 80 ± 4).
Peak oxygen consumption (VO2 peak, power) during a symptom-limited cardiopulmonary stress test, distance walked in a 6-minute walk test (6MWT, resistance), and peak torque (strength) using an isokinetic dynamometer, were assessed at baseline and at discharge from a 4-week supervised training program.
Indexes of physical performance improved from baseline to discharge (VO2 peak, 10.9%; 6MWT, 11.0%; peak torque, 11.5%). Baseline performance was independently associated with changes in all three indexes, with higher baseline values predicting less improvement (VO2 peak: OR=0.86, 95% confidence interval (CI)=0.77-0.97; 6MWT: OR= 0.99, 95% CI=0.99-1.00; peak torque: OR=0.96, 95% CI=0.94-0.98).
An exercise-based CR program was associated with improvement in all domains of physical performance even in older adults after an acute coronary event or cardiac surgical intervention, particularly in those with poorer baseline performance.
评估心脏康复(CR)的效果,并确定近期发生心脏事件的老年患者系列中CR后功能能力变化的预测因素。
观察性研究。
医院内CR单元。
75岁及以上的个体,在急性冠状动脉事件(不稳定型心绞痛、急性心肌梗死)或心脏手术后(冠状动脉搭桥术、心脏瓣膜置换或修复)被转诊至门诊CR单元(N = 160,平均年龄80±4)。
在基线时以及从为期4周的监督训练计划出院时,评估症状限制心肺应激试验期间的峰值耗氧量(VO2峰值,功率)、6分钟步行试验中的步行距离(6MWT,阻力)以及使用等速测力计测量的峰值扭矩(力量)。
身体表现指标从基线到出院有所改善(VO2峰值,10.9%;6MWT,11.0%;峰值扭矩,11.5%)。基线表现与所有三项指标的变化独立相关,基线值越高,改善越少(VO2峰值:OR = 0.86,95%置信区间(CI)= 0.77 - 0.97;6MWT:OR = 0.99,95% CI = 0.99 - 1.00;峰值扭矩:OR = 0.96,95% CI = 0.94 - 0.98)。
即使是在急性冠状动脉事件或心脏手术干预后的老年人中,基于运动的CR计划也与身体表现所有领域的改善相关,尤其是在基线表现较差的患者中。