Fujiki M, Miyamoto S, Zenda S, Sakuraba M
Division of Plastic and Reconstructive Surgery,National Cancer Center Hospital East,Kashiwa,Chiba.
Division of Plastic and Reconstructive Surgery,National Cancer Center,Tokyo,Japan.
J Laryngol Otol. 2016 Sep;130(9):865-72. doi: 10.1017/S0022215116008720. Epub 2016 Aug 17.
This study evaluated the longitudinal and long-term effects of radiotherapy on swallowing function after tongue reconstruction.
The study comprised 16 patients who had: undergone glossectomy and tongue reconstruction with free flap transfer, received adjuvant radiotherapy, and survived without recurrence for at least 1 year. Swallowing function, as indicated by tolerance of oral intake, was evaluated before radiotherapy, at radiotherapy completion, and at 6 and 12 months after radiotherapy completion.
Before radiotherapy, all patients could tolerate oral intake. At radiotherapy completion, only three patients could consume all nutrition orally. However, swallowing function improved over time, and by 12 months after radiotherapy completion it had returned nearly to that before radiotherapy.
Acute dysphagia due to radiotherapy after tongue reconstruction is severe, but can improve gradually. Multidisciplinary support of patients during percutaneous endoscopic gastrostomy dependence is important to improve long-term functional outcomes.
本研究评估了放疗对舌重建术后吞咽功能的纵向和长期影响。
该研究纳入了16例患者，这些患者接受了舌切除术并采用游离皮瓣移植进行舌重建，接受了辅助放疗，且存活且无复发至少1年。根据经口摄入耐受性评估吞咽功能，在放疗前、放疗结束时以及放疗结束后6个月和12个月进行评估。
放疗前，所有患者均能耐受经口摄入。放疗结束时，只有3例患者能够经口摄入所有营养。然而，吞咽功能随时间改善，放疗结束后12个月时几乎恢复到放疗前水平。
舌重建术后放疗引起的急性吞咽困难严重，但可逐渐改善。在经皮内镜下胃造口术依赖期间对患者进行多学科支持对于改善长期功能结局很重要。
Zotero 插件