Lohneis P, Nogai A, Niehues S M, Jöhrens K, Anagnostopoulos I
Institut für Pathologie, Charité-Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117, Berlin, Deutschland.
Medizinische Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie, Charité-Universitätsmedizin Berlin, Berlin, Deutschland.
Pathologe. 2016 Nov;37(6):568-572. doi: 10.1007/s00292-016-0213-5.
During the preoperative diagnostics of an 80-year-old male patient prior to a planned endarterectomy, an unclear space-occupying lesion was detected in the right nasopharyngeal cavity. It proved to be a dense soft tissue space-occupying lesion of the right maxillary sinus. The histological investigations revealed a partially necrotically decomposed malignant tumor below normal respiratory mucosa free from dysplasia. This case demonstrates the difficulties in differential diagnostics, particularly involving (aberrant) expression of cytokeratin.
在一名80岁男性患者计划进行动脉内膜切除术的术前诊断过程中,在右侧鼻咽腔发现了一个不明占位性病变。结果证明它是右侧上颌窦的一个致密软组织占位性病变。组织学检查显示,在无发育异常的正常呼吸黏膜下方有一个部分坏死分解的恶性肿瘤。该病例显示了鉴别诊断的困难,特别是涉及细胞角蛋白的(异常)表达。