Marin M L, Perzin K H, Markowitz A M
Department of Surgery, Columbia Presbyterian Medical Center, New York, N.Y. 10032.
J Thorac Cardiovasc Surg. 1989 Aug;98(2):234-8.
Elastofibroma dorsi was diagnosed in seven patients at the Columbia-Presbyterian Medical Center between 1976 and 1986. The ages of the patients ranged from 6 to 79 years (mean 49.3 years). No sex predominance was seen. Five cases of unilateral subscapular tumor and two cases of bilateral masses were identified. Four patients had pain with arm motion, and the remaining patients were free of symptoms. A nonencapsulated soft tissue mass elevating the scapula was identified by computed tomography. Incisional biopsy was performed in all cases, followed by local excision of the tumor. On gross examination, these lesions were firm and rubbery. Histologic evaluation demonstrated a slightly hypercellular fibrous tissue that contained variable numbers of fragmented elastic fibers. All patients with symptomatic tumors had complete relief of their pain after the operation. No recurrences were observed. Clinically, elastofibroma may mimic sarcoma and fibromatosis (extraabdominal desmoid tumors). Whether elastofibroma is a true neoplasm or a reactive fibrous lesion that produces not only collagen, but also abnormal elastic fibers, has been the subject of controversy and remains undetermined.
1976年至1986年间,哥伦比亚长老会医学中心确诊了7例背部弹力纤维瘤患者。患者年龄从6岁至79岁不等(平均49.3岁)。未发现性别优势。发现5例单侧肩胛下肿瘤和2例双侧肿块。4例患者手臂活动时疼痛,其余患者无症状。计算机断层扫描发现一个抬高肩胛骨的无包膜软组织肿块。所有病例均进行了切开活检,随后对肿瘤进行局部切除。大体检查时,这些病变质地坚硬且有弹性。组织学评估显示纤维组织细胞轻度增多,含有数量不等的断裂弹性纤维。所有有症状肿瘤的患者术后疼痛完全缓解。未观察到复发情况。临床上,弹力纤维瘤可能类似肉瘤和纤维瘤病(腹外硬纤维瘤)。弹力纤维瘤是一种真正的肿瘤还是一种不仅产生胶原蛋白还产生异常弹性纤维的反应性纤维病变,一直存在争议且尚无定论。