Tomazic Peter Valentin, Gerstenberger Claus, Rant Bettina, Nemetz Ulrike, Brezjak-Kahlert Christiana, Wolf Axel, Freudenschuss Kurt, Wolf Gerald
Department of General Otorhinolaryngology-Head and Neck Surgery, University Hospital Graz, Medical University Graz, Auenbruggerplatz 26, 8036 Graz, Austria.
Ear Nose Throat J. 2016 Aug;95(8):344-52.
Inferior turbinate hypertrophy is a common cause of nasal obstruction. We conducted a prospective study to correlate subjective and objective parameters in assessing the effectiveness of radiofrequency ablation (RFA). Our initial study population was made up of 10 patients who presented with nasal obstruction; 1 patient was lost to follow-up, leaving us with 7 women and 2 men, aged 26 to 65 years (mean: 37.9 ± 12.8), and 16 turbinates (7 bilateral, 1 right, and 1 left). Visual analogue scale (VAS) scores, Nasal Obstruction and Symptom Evaluation (NOSE) questionnaire scores, rhinomanometry results, and CT- and MRI-based volumetry were obtained before RFA and 6 months afterward. For the subjective parameters, the mean pre- and postoperative VAS scores for the 16 turbinates were 6.6 ± 1.6 and 2.8 ± 2.0 (p < 0.001), respectively, and the mean pre- and postoperative NOSE scores in the 9 patients were 15.3 ± 3.1 and 5.8 ± 5.4 (p = 0.003). For the objective parameters, the mean pre- and postoperative rhinomanometry values at 150 Pa were 241.0 ± 141.3 and 265.4 ± 157.3 ml/sec (p = 0.403), and the mean pre- and postoperative volumetry values were 5.3 ± 2.5 and 5.0 ± 2.1 cm(3) (p = 0.551). Note that only the differences in the subjective parameters reached statistical significance. RFA of the inferior turbinates as a treatment for nasal obstruction is safe and easy. However, our study found a discrepancy between the subjective and objective outcomes parameters, as the former showed highly significant improvement and the latter showed only a slight improvement that did not reach statistical significance.
下鼻甲肥大是鼻塞的常见原因。我们进行了一项前瞻性研究,以关联主观和客观参数来评估射频消融(RFA)的有效性。我们最初的研究对象包括10名出现鼻塞的患者;1名患者失访,最终剩下7名女性和2名男性,年龄在26至65岁之间(平均:37.9±12.8),共16个鼻甲(7对双侧,1个右侧,1个左侧)。在RFA术前及术后6个月获取视觉模拟量表(VAS)评分、鼻阻塞与症状评估(NOSE)问卷评分、鼻阻力测量结果以及基于CT和MRI的体积测量数据。对于主观参数,16个鼻甲术前和术后的平均VAS评分分别为6.6±1.6和2.8±2.0(p<0.001),9名患者术前和术后的平均NOSE评分分别为15.3±3.1和5.8±5.4(p = 0.003)。对于客观参数,150 Pa时术前和术后的平均鼻阻力测量值分别为241.0±141.3和265.4±157.3 ml/秒(p = 0.403),术前和术后的平均体积测量值分别为5.3±2.5和5.0±2.1 cm³(p = 0.551)。请注意,只有主观参数的差异具有统计学意义。下鼻甲射频消融作为鼻塞的一种治疗方法安全且简便。然而,我们的研究发现主观和客观结果参数之间存在差异,前者显示出高度显著的改善,而后者仅显示出轻微改善且未达到统计学意义。