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肾移植术后泌尿外科并发症的微创手术治疗进展与现状

The development and current status of minimally invasive surgery to manage urological complications after renal transplantation.

作者信息

Sabnis Ravindra B, Singh Abhishek G, Ganpule Arvind P, Chhabra Jaspreet S, Tak Gopal R, Shah Jaimin H

机构信息

Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat, India.

出版信息

Indian J Urol. 2016 Jul-Sep;32(3):186-91. doi: 10.4103/0970-1591.185100.

Abstract

INTRODUCTION

In the past, urological complications after renal transplantation were associated with significant morbidity. With the development and application of endourological procedures, it is now possible to manage these cases with minimally invasive techniques.

MATERIALS AND METHODS

A MEDLINE search for articles published in English using key words for the management of urological complications after renal transplantation was undertaken. Forty articles were selected and reviewed.

RESULTS

The incidence of urological complications postrenal transplantation was reported to be 2-13%. Ureteric leaks occurred in up to 8.6%, and 55% were managed endourologically. The incidence of lymphocele was as high as 20%, and less that 12% of the cases required treatment. Ureteric stricture was the most common complication, and endourological management was successful in 50-70%. The occurrence of complicated vesicoureteral reflux was 4.5%, and 90% of low-grade reflux cases were successfully treated with deflux injections. Stones and obstructive voiding dysfunction occurred in about 1% of kidney transplant recipients.

CONCLUSION

Minimally invasive techniques have a critical role in the management of urological complications after renal transplantation. Urinary leakage should be managed with complete decompression. Percutaneous drainage should be the first line of treatment for lymphocele that is symptomatic or causing ureteric obstruction. Laparoscopic lymphocele deroofing is successful in aspiration-resistant cases. Deflux is highly successful for the management of complicated low-grade kidney transplant reflux. The principles of stone management in a native solitary kidney are applied to the transplanted kidney. Early identification and treatment of bladder outlet obstruction after renal transplantation can prevent urinary leakage and obstructive uropathy.

摘要

引言

过去,肾移植后的泌尿外科并发症与显著的发病率相关。随着腔内泌尿外科手术的发展和应用,现在可以用微创技术处理这些病例。

材料与方法

利用肾移植后泌尿外科并发症管理的关键词在MEDLINE上检索英文发表的文章。筛选并审阅了40篇文章。

结果

据报道,肾移植后泌尿外科并发症的发生率为2%-13%。输尿管漏发生率高达8.6%,其中55%通过腔内泌尿外科方法处理。淋巴囊肿发生率高达20%,不到12%的病例需要治疗。输尿管狭窄是最常见的并发症,腔内泌尿外科处理成功率为50%-70%。复杂性膀胱输尿管反流的发生率为4.5%,90%的低度反流病例通过注射交联透明质酸钠成功治疗。肾结石和梗阻性排尿功能障碍在约1%的肾移植受者中发生。

结论

微创技术在肾移植后泌尿外科并发症的处理中起关键作用。尿漏应通过完全减压处理。对于有症状或导致输尿管梗阻的淋巴囊肿,经皮引流应作为一线治疗方法。腹腔镜下淋巴囊肿去顶术在抗抽吸的病例中取得成功。交联透明质酸钠对于处理复杂性低度肾移植反流非常成功。处理移植肾结石的原则与处理单肾肾结石的原则相同。肾移植后早期识别和治疗膀胱出口梗阻可预防尿漏和梗阻性肾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7274/4970388/b7730f8cb1c2/IJU-32-186-g001.jpg

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