Mason Sarah, Van Hemelrijck Mieke, Chandra Ashish, Brown Christian, Cahill Declan
King's College London, Division of Cancer Studies, Cancer Epidemiology Group, London, UK.
King's Health Partners, London SE1 9RT, UK.
Ecancermedicalscience. 2016 Jul 6;10:651. doi: 10.3332/ecancer.2016.651. eCollection 2016.
To document the learning curve for the laparoscopic radical prostatectomy (LRP) procedure and discuss the optimal usage of prospectively documented outcome data for reporting a surgeon's performance.
Using prospectively collected data from the first series of patients to undergo LRP by two surgeons in the same institution, linear and logistic regression multivariate analyses per 25 patients were carried out to graphically represent the surgical learning curve for operative time, blood loss, complications, length of stay (LOS), and positive margins. Surgeon A carried out 275 operations between 2003-2009; Surgeon B carried out 225 between 2008-2012.
Learning curves showing continuous improvement of each of the above outcomes were demonstrated for both cohorts. For surgeon A, a plateau was observed for LOS and T2 positive margins after 100 and 150 surgeries respectively. No such plateau was observed for surgeon B.
On documenting these learning curves and discussion of the reporting methods used, we concluded that the most informative outcome measure, with the least potential observer bias was T2 positive margins. Whether as a single measure or in combination with others, this has potential for use as an objective outcome representative of improvement in a surgeon's skill over time.
记录腹腔镜根治性前列腺切除术(LRP)的学习曲线,并讨论前瞻性记录的结果数据在报告外科医生手术表现方面的最佳应用。
利用同一机构中两位外科医生对首批接受LRP手术患者的前瞻性收集数据,每25例患者进行线性和逻辑回归多变量分析,以图形方式呈现手术时间、失血量、并发症、住院时间(LOS)和切缘阳性情况的手术学习曲线。外科医生A在2003年至2009年间进行了275例手术;外科医生B在2008年至2012年间进行了225例手术。
两个队列均显示出上述各项结果持续改善的学习曲线。对于外科医生A,分别在100例和150例手术后,观察到LOS和T2期切缘阳性出现平台期。外科医生B未观察到此类平台期。
在记录这些学习曲线并讨论所使用的报告方法后,我们得出结论,信息最丰富且潜在观察者偏差最小的结果指标是T2期切缘阳性。无论作为单一指标还是与其他指标结合,这都有可能作为代表外科医生技能随时间提高的客观结果。