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[营养干预在结直肠癌手术快速康复计划中的效果:系统评价]

[Effects of a nutritional intervention in a fast-track program for a colorectal cancer surgery: systematic review].

作者信息

Wanden-Berghe Carmina, Sanz-Valero Javier, Arroyo-Sebastián Antonio, Cheikh-Moussa Kamila, Moya-Forcen Pedro

机构信息

University General Hospital of Alicante. ISABIAL-FISABIO. Alicante.

出版信息

Nutr Hosp. 2016 Jul 19;33(4):402. doi: 10.20960/nh.402.

Abstract

UNLABELLED

Introducción: Preoperative nutritional status (NS) has consequences on postoperative (POSTOP) recovery. Our aim was to systematically review the nutritional interventions (NI) in Fast-Track protocols for colorectal cancer surgery and assess morbidity-mortality and patient´s recovery.

METHOD

Systematic review of scientific literature after consulting bibliographic databases: Medline, The Cochrane Library, Scopus, Embase, Web of Science, Institute for Scientific Information, Latin American and Caribbean Health Sciences Literature, The Cumulative Index to Nursing and Allied Health Literature. MeSH Descriptors: "Colorectal Surgery", "Fast-Track", "Perioperative Care", "Nutrition Therapy" and "Enhanced recovery programme". Filters: "Humans", Adult (19+ years) and "Clinical Trial". Variables POSTOP outcomes: bowel recovery (BR), hospital stay (HS), complications and death.

RESULTS

Selected studies, 27, had good or excellent methodological quality. From 25 to 597 patients were included. Aged between 16-94 years, men were predominant in 66.6%. NS was evaluated in 13 studies; 7 by Body Mass Index while one by Subjective Global Assessment. One presented POSTOP data. Fast-Track groups had solids, liquids or supplements (SS) in prior 2-8 hours. SS were high in carbohydrates, immune-nutrients and non-residue. Free liquids, solids and SS intake was allowed in POSTOP. Half traditional groups fasted between 3-12 hours and resumed POSTOP food intake progressively.

CONCLUSIONS

Fast-Track groups had early BR (p < 0.01). Traditional groups had more infections episodes, deaths and a longer HS. Great variability between NI but had a common item; early intake. Although was seen patient's recovery. Future studies with detailed NI characteristics are need. Nutritional status must be assessed for a higher acknowledgement of NI impact.

摘要

未标注

引言:术前营养状况对术后恢复有影响。我们的目的是系统回顾结直肠癌手术快速康复方案中的营养干预措施,并评估发病率、死亡率和患者恢复情况。

方法

在查阅文献数据库后对科学文献进行系统回顾:医学文献数据库、考克兰图书馆、Scopus、Embase、科学引文索引、科学信息研究所、拉丁美洲和加勒比卫生科学文献、护理及相关健康文献累积索引。医学主题词描述符:“结直肠手术”、“快速康复”、“围手术期护理”、“营养治疗”和“强化康复计划”。筛选条件:“人类”、成年人(19岁及以上)和“临床试验”。术后结果变量:肠道恢复、住院时间、并发症和死亡。

结果

选定27项研究,其方法学质量良好或优秀。纳入患者25至597例。年龄在16 - 94岁之间,男性占66.6%。13项研究评估了营养状况;7项通过体重指数评估,1项通过主观全面评定法评估。1项呈现了术后数据。快速康复组在术前2 - 8小时摄入固体食物、液体或补充剂。补充剂富含碳水化合物、免疫营养素且无残渣。术后允许自由摄入液体、固体食物和补充剂。半数传统组禁食3 - 12小时,术后逐渐恢复食物摄入。

结论

快速康复组肠道恢复早(p < 0.01)。传统组感染发作更多、死亡病例更多且住院时间更长。营养干预措施之间差异很大,但有一个共同特点;早期摄入。尽管观察到了患者的恢复情况。需要开展具有详细营养干预特征的未来研究。必须评估营养状况,以更好地认识营养干预的影响。

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