Dorier A, Piery Y, Bacques C
Anat Histol Embryol. 1989 Jun;18(2):183-92. doi: 10.1111/j.1439-0264.1989.tb00595.x.
The study, through optical and scanning microscopy, of various developmental stages, from the 24th day of gestation to the 13th day after birth, shows a quick development of the structures of the caecal and colic mucosal layers to the adult forms, from the very first week of postnatal life. The distal part of the colon is full-grown before the other parts of the alimentary canal, and is particularly rich in mucous cells. The caecum is the place where an early lymphoid defense is provided, from the 30th day of gestation.
该研究通过光学显微镜和扫描显微镜,对从妊娠第24天到出生后第13天的各个发育阶段进行观察,结果显示,从出生后第一周开始,盲肠和结肠黏膜层的结构迅速发育为成年形态。结肠远端在消化道其他部分之前就已发育成熟,且黏液细胞特别丰富。从妊娠第30天起,盲肠就是提供早期淋巴防御的部位。