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带窗安那康达覆膜支架在肾旁、肾上及IV型胸腹主动脉瘤血管内治疗中的手术及中期结果

Operative and Midterm Outcomes of the Fenestrated Anaconda Stent-Graft in the Endovascular Treatment of Juxtarenal, Suprarenal, and Type IV Thoracoabdominal Aortic Aneurysms.

作者信息

Kotelis Drosos, Schleimer Karina, Foldenauer Christina, Jalaie Houman, Grommes Jochen, Jacobs Michael J, Kalder Johannes

机构信息

European Vascular Center Aachen-Maastricht, Department of Vascular Surgery, RWTH Aachen University Hospital, Aachen, Germany.

European Vascular Center Aachen-Maastricht, Department of Vascular Surgery, RWTH Aachen University Hospital, Aachen, Germany

出版信息

J Endovasc Ther. 2016 Dec;23(6):930-935. doi: 10.1177/1526602816667281. Epub 2016 Aug 29.

Abstract

PURPOSE

To report operative and midterm outcomes of fenestrated endovascular aneurysm repair (FEVAR) with the Anaconda device.

METHODS

A retrospective analysis was conducted of 39 consecutive patients (median age 74 years; 36 men) treated with the fenestrated Anaconda stent-graft between July 2011 and December 2015 at a single center. Indications for FEVAR were abdominal aortic aneurysms (AAAs) with neck anatomy unsuitable for a standard stent-graft. Median infrarenal neck length was 4 mm (range 0-9). Four (10%) patients presented with type IV thoracoabdominal aortic aneurysm (TAAA), 12 (31%) with suprarenal aneurysms, and 23 (59%) with juxtarenal aneurysms. Four (10%) patients had previous infrarenal aortic repair. Five (13%) patients had an infrarenal neck angulation >60°. A total of 106 fenestrations were incorporated into the stent-grafts (73 renal arteries, 25 superior mesenteric arteries, and 8 celiac trunks). Technical success, perioperative and midterm mortality and morbidity, target vessel patency, endoleaks, and reinterventions were documented.

RESULTS

Technical success was 95% (37/39). Three (8%) patients died in-hospital from mesenteric embolism in 2 and renal artery rupture with consequent multiorgan failure in 1. Two (5%) patients suffered an intraoperative embolic stroke. During a median follow-up of 33 months (range 4-55), adjunctive maneuvers were performed in 9 (23%) patients, including reintervention for type II endoleak with enlarged aneurysm sac in 2 (5%). Four additional patients died of causes unrelated to the aortic pathology (overall mortality 18%). In 34 (94%) of the 36 patients seen in follow-up, aneurysm sac size was stable or decreased. Target vessel stent patency was 99% (95/96).

CONCLUSION

FEVAR with the Anaconda device delivers satisfactory short-term technical and clinical success rates in patients with juxtarenal, suprarenal, and type IV TAAA. Midterm efficacy and durability with respect to aneurysm sac regression and target vessel patency appear very good. Overall mortality and the need for reintervention were significant in this patient cohort.

摘要

目的

报告使用Anaconda装置进行开窗式血管腔内动脉瘤修复术(FEVAR)的手术及中期结果。

方法

对2011年7月至2015年12月在单一中心接受开窗式Anaconda覆膜支架治疗的39例连续患者(中位年龄74岁;36例男性)进行回顾性分析。FEVAR的适应证为颈部解剖结构不适合标准覆膜支架的腹主动脉瘤(AAA)。肾下颈部中位长度为4mm(范围0 - 9mm)。4例(10%)患者为IV型胸腹主动脉瘤(TAAA),12例((31%)为肾上动脉瘤,23例(59%)为肾旁动脉瘤。4例(10%)患者既往有肾下主动脉修复史。5例(13%)患者肾下颈部成角>60°。支架移植物共包含106个开窗(73个肾动脉、25个肠系膜上动脉和8个腹腔干)。记录技术成功率、围手术期及中期死亡率和发病率、靶血管通畅情况、内漏及再次干预情况。

结果

技术成功率为95%(37/39)。3例(8%)患者住院期间死亡,2例死于肠系膜栓塞,1例死于肾动脉破裂并随之发生多器官功能衰竭。2例(5%)患者术中发生栓塞性卒中。在中位随访33个月(范围4 - 55个月)期间,9例(23%)患者进行了辅助操作,其中2例(5%)因II型内漏伴动脉瘤囊增大而进行再次干预。另外4例患者死于与主动脉病变无关的原因(总死亡率18%)。在随访的36例患者中的34例(94%)中,动脉瘤囊大小稳定或缩小。靶血管支架通畅率为99%(95/96)。

结论

对于肾旁、肾上和IV型TAAA患者,使用Anaconda装置进行FEVAR可获得令人满意的短期技术和临床成功率。在动脉瘤囊消退和靶血管通畅方面,中期疗效和耐久性似乎非常好。在该患者队列中,总体死亡率和再次干预的需求较高。

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