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基于使用Trevo取栓支架对急性缺血性中风进行血管内血栓切除术时对血栓质量评估的治疗方案。

Treatment protocol based on assessment of clot quality during endovascular thrombectomy for acute ischemic stroke using the Trevo stent retriever.

作者信息

Ishikawa Kojiro, Ohshima Tomotaka, Nishihori Masahiro, Imai Tasuku, Goto Shunsaku, Yamamoto Taiki, Nishizawa Toshihisa, Shimato Shinji, Kato Kyozo

机构信息

Department of Neurosurgery, Kariya Toyota General Hospital, Kariya, Japan.

出版信息

Nagoya J Med Sci. 2016 Aug;78(3):255-65.

Abstract

The optional endovascular approach for acute ischemic stroke is unclear. The Trevo stent retriever can be used as first-line treatment for fast mechanical recanalization. The authors developed a treatment protocol for acute ischemic stroke based on the assessment of clot quality during clot removal with the Trevo. This prospective single-center study included all patients admitted for acute ischemic stroke between July 2014 and February 2015, who underwent emergency endovascular treatment. According to the protocol, the Trevo was used for first-line treatment. Immediately after the Trevo was deployed, the stent delivery wire was pushed to open the stent by force (ACAPT technique). Clot quality was assessed on the basis of the perfusion status after deployment of the Trevo; continued occlusion or immediate reopening either reoccluded or maintained after the stent retriever had been in place for 5 min. If there was no obvious clot removal after the first pass with the Trevo, according to the quality of the clot, either a second pass was performed or another endovascular device was selected. Twelve consecutive patients with acute major cerebral artery occlusion were analyzed. Thrombolysis in cerebral infarction score 2b and 3 was achieved in 11 patients (91.7%) and 9 (75%) had a good clinical outcome after 90 days based on a modified Rankin scale score ≤ 2. Symptomatic intracranial hemorrhage occurred in 1 patient (8.3%). The overall mortality rate was 8.3%. Endovascular thrombectomy using the Trevo stent retriever for first-line treatment is feasible and effective.

摘要

急性缺血性卒中的选择性血管内治疗方法尚不清楚。Trevo支架取栓器可作为快速机械再通的一线治疗方法。作者基于使用Trevo取栓过程中对血栓质量的评估,制定了一种急性缺血性卒中的治疗方案。这项前瞻性单中心研究纳入了2014年7月至2015年2月期间因急性缺血性卒中入院并接受急诊血管内治疗的所有患者。根据该方案,Trevo被用作一线治疗。在部署Trevo后,立即用力推送支架输送钢丝以打开支架(ACAPT技术)。根据Trevo部署后的灌注状态评估血栓质量;持续闭塞或立即再通,在支架取栓器放置5分钟后要么再次闭塞要么保持通畅。如果使用Trevo首次取栓后没有明显的血栓清除,根据血栓质量,要么进行第二次取栓,要么选择另一种血管内装置。对连续12例急性大脑中动脉闭塞患者进行了分析。11例患者(91.7%)达到脑梗死溶栓评分2b和3分,90天后基于改良Rankin量表评分≤2,9例(75%)患者获得良好的临床结局。1例患者(8.3%)发生有症状性颅内出血。总死亡率为8.3%。使用Trevo支架取栓器进行一线治疗的血管内血栓切除术是可行且有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7155/4995271/d9f09b7ee518/2186-3326-78-0255-g001.jpg

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