Mohla Aditi, Khan Kamron, Kasilian Melissa, Michaelides Michel
Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Moorfields Eye Hospital NHS Foundation Trust, London, UK UCL Institute of Ophthalmology, London, UK.
BMJ Case Rep. 2016 Sep 1;2016:bcr2016216453. doi: 10.1136/bcr-2016-216453.
We describe the management of a woman aged 52 years with molecularly confirmed Sorsby fundus dystrophy, who presented with acute visual deterioration in her right eye. Fundus examination identified a right macular lesion suggestive of a choroidal neovascular membrane (CNVM). Optical coherence tomography angiography (OCTA) confirmed the presence of a CNVM. She was treated with 2 monthly intravitreal injections of bevacizumab, associated with OCTA evidence of regression of the CNVM and improvement in her visual acuity. OCTA is a novel, non-invasive method of imaging the retinal vasculature. Images are acquired rapidly, with no associated side effects, offering advantages over the current gold standard technique-fundus fluorescein angiography.
我们描述了一名52岁女性分子确诊为索斯比眼底营养不良的病例,她右眼出现急性视力下降。眼底检查发现右黄斑病变,提示脉络膜新生血管膜(CNVM)。光学相干断层扫描血管造影(OCTA)证实存在CNVM。她接受了每月2次玻璃体内注射贝伐单抗治疗,OCTA显示CNVM消退且视力改善。OCTA是一种新型的、非侵入性的视网膜血管成像方法。图像采集迅速,无相关副作用,比当前的金标准技术——眼底荧光血管造影具有优势。