Suppr超能文献

耻骨切除为患有耻骨骨髓炎并伴有从泌尿道至耻骨联合瘘管的前列腺癌幸存者提供了客观的疼痛控制。

Pubic Bone Resection Provides Objective Pain Control in the Prostate Cancer Survivor With Pubic Bone Osteomyelitis With an Associated Urinary Tract to Pubic Symphysis Fistula.

作者信息

Lavien Garjae, Chery Godefroy, Zaid Uwais B, Peterson Andrew C

机构信息

Department of Urology, Regions Hospital, St Paul, MN; Division of Urology, Genitourinary Cancer Survivorship Program, Duke University Medical Center, Durham, NC.

Division of Urology, Genitourinary Cancer Survivorship Program, Duke University Medical Center, Durham, NC.

出版信息

Urology. 2017 Feb;100:234-239. doi: 10.1016/j.urology.2016.08.035. Epub 2016 Aug 31.

Abstract

OBJECTIVE

To investigate pain intensity perception in prostate cancer survivors with pubic bone osteomyelitis with an associated urinary tract to pubic symphysis fistula before and after definitive surgical management.

MATERIALS AND METHODS

We performed a review of an institutional review board-approved database of prostate cancer survivors with pubic bone osteomyelitis from 2010 to 2015. Demographic and clinical data were extracted. Pain scores were assessed in patients at varying points before and after definitive treatment using an 11-point numeric rating scale. Statistical analysis was performed using a Wilcoxon signed-rank test and NcNemar's test.

RESULTS

We identified 16 patients with a median age of 72 who met inclusion criteria. Chronic narcotic use for pain management was noted in 6 of 16 (37.5%) patients preoperatively. No statistical difference was identified between the pain score at the time of diagnosis and after completion of conservative measures (5.5 vs 5.5, P = .76). A statistically significant decrease in median pain score at the first follow-up appointment was seen compared to the preoperative pain score (0 vs. 5.5, P = .0005). At a median follow-up of 9.4 months (interquartile range 3.7-16.5), a sustained decrease in the median pain intensity score was noted in our cohort compared to their preoperative baseline pain score (5.5 vs 0, P = .0005) and pain score at the time of diagnosis (5.5 vs 0, P = .004.) CONCLUSION: Pubic bone resection provides immediate and sustained improvement in pain intensity perception in the prostate cancer survivor with pubic bone osteomyelitis with an associated urinary tract to pubic symphysis fistula.

摘要

目的

研究患有耻骨骨髓炎并伴有泌尿道至耻骨联合瘘管的前列腺癌幸存者在确定性手术治疗前后的疼痛强度感知情况。

材料与方法

我们对2010年至2015年机构审查委员会批准的患有耻骨骨髓炎的前列腺癌幸存者数据库进行了回顾。提取了人口统计学和临床数据。使用11点数字评分量表在确定性治疗前后的不同时间点对患者的疼痛评分进行评估。采用Wilcoxon符号秩检验和NcNemar检验进行统计分析。

结果

我们确定了16例符合纳入标准的患者,中位年龄为72岁。术前16例患者中有6例(37.5%)因疼痛管理而长期使用麻醉剂。诊断时的疼痛评分与保守治疗完成后的疼痛评分之间未发现统计学差异(5.5对5.5,P = 0.76)。与术前疼痛评分相比,首次随访时中位疼痛评分有统计学显著下降(0对5.5,P = 0.0005)。在中位随访9.4个月(四分位间距3.7 - 16.5)时,与术前基线疼痛评分相比,我们队列中的中位疼痛强度评分持续下降(5.5对0,P = 0.0005),与诊断时的疼痛评分相比也有下降(5.5对0,P = 0.004)。结论:耻骨切除术能使患有耻骨骨髓炎并伴有泌尿道至耻骨联合瘘管的前列腺癌幸存者的疼痛强度感知立即且持续改善。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验