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[不同动脉压水平大鼠的神经肌肉兴奋性和疼痛敏感性]

[Neuromuscular excitation and pain sensitivity of rats with various levels of arterial pressure].

作者信息

Bachmanov A A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1989 Apr;75(4):486-92.

PMID:2759285
Abstract

Responses to electric shock stimulation were studied in spontaneously hypertensive (SHR) and normotensive (WKY) rats. Neuro-muscular excitability and the pain thresholds were higher in the SHR rats. The decrease in the pain sensitivity seemed to be connected with changes of neuro-muscular excitability in hypertensive animals. The SHR rats were more active in new environment. Weak electric shocks reduced motor activity in the SHR rats more than in the WKY rats. Strong electric shocks enhanced motor activity and eliminated the strain and sex differences. The painful electric stimulation elicited a more obvious jumping activity in the SHR rats and a more active vocalisation in the WKY rats.

摘要

研究了自发性高血压大鼠(SHR)和正常血压大鼠(WKY)对电击刺激的反应。SHR大鼠的神经肌肉兴奋性和痛阈较高。高血压动物痛觉敏感性的降低似乎与神经肌肉兴奋性的变化有关。SHR大鼠在新环境中更活跃。弱电击对SHR大鼠运动活动的降低作用比对WKY大鼠更明显。强电击增强了运动活动并消除了品系和性别差异。疼痛性电刺激在SHR大鼠中引发更明显的跳跃活动,在WKY大鼠中引发更活跃的发声。

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