Subasinghe Duminda, Navarathna Navarathna Mudiyanselage Meththananda, Samarasekera Dharmabandhu Nandadeva
Duminda Subasinghe, Navarathna Mudiyanselage Meththananda Navarathna, Dharmabandhu Nandadeva Samarasekera, Department of Surgery, Faculty of Medicine, University Surgical Unit, the National Hospital of Sri Lanka, Colombo 08, Sri Lanka.
World J Gastrointest Pharmacol Ther. 2016 Aug 6;7(3):447-52. doi: 10.4292/wjgpt.v7.i3.447.
To analyze the frequency and severity of faecal incontinence (FI) and its effect on the quality of life (QOL) in inflammatory bowel disease (IBD) patients.
All patients who attended surgical and medical gastroenterology outpatient clinics in a tertiary care center with an established diagnosis of either ulcerative colitis (UC) or Crohn's disease (CD) over a period of 10 mo were included in this study. Before enrollment into the study, the patients were explained about the study and informed consent was obtained. The patients with unidentified colitis were excluded. The data on demographics, disease characteristics, FI (Vaizey score), and quality of life (IBD-Q) were collected. Data were analyzed using SPSS version 21.
There were 184 patients (women = 101, 54.9%; UC = 153, 83.2%) with a female preponderance for UC (male/female ratio = 1:1.5) and a male preponderance for CD (male/female = 2:1). Forty-eight (26%) patients reported symptoms of FI. Among the patients with FI, 70.8% were women (n = 34) and 29.2% were men (n = 14) with an average age of 52.7 years (range, 20-78 years). Average age of onset of FI was 48.6 (range, 22-74) years. Ten percent (n = 5) reported regular FI. Incontinence to flatus was seen in 33.3% (n = 16), to liquid faeces in 56.2% (n = 27), to solid faeces in 6.2% (n = 3) and to all three in 4.1% (n = 2). Twenty-one percent (n = 10) complained of disruption of their physical and social activity. There was no association between FI and type of IBD. Significant associations were found between FI and age (P = 0.005) and gender (P < 0.001). QOL in our cohort of patients was significantly affected by FI.
In our study, nearly a quarter of patients reported FI. There was a significant correlation between FI and QOL. Therefore, enquiring about FI in IBD patients can lead to identification of this debilitating condition. This will enable early referral for continence care in this group of patients.
分析炎症性肠病（IBD）患者粪便失禁（FI）的发生频率和严重程度及其对生活质量（QOL）的影响。
本研究纳入了在一家三级医疗中心的外科和内科胃肠病门诊就诊的所有患者，这些患者在10个月内被确诊为溃疡性结肠炎（UC）或克罗恩病（CD）。在纳入研究之前，向患者解释了该研究并获得了知情同意。排除未确诊的结肠炎患者。收集了人口统计学、疾病特征、FI（Vaizey评分）和生活质量（IBD-Q）的数据。使用SPSS 21版进行数据分析。
共有184例患者（女性 = 101例，占54.9%；UC = 153例，占83.2%），UC以女性居多（男/女比例 = 1:1.5），CD以男性居多（男/女 = 2:1）。48例（26%）患者报告有FI症状。在有FI的患者中，70.8%为女性（n = 34），29.2%为男性（n = 14），平均年龄为52.7岁（范围为20 - 78岁）。FI的平均发病年龄为48.6岁（范围为22 - 74岁）。10%（n = 5）报告有持续性FI。33.3%（n = 16）出现排气失禁，56.2%（n = 27）出现稀便失禁，6.2%（n = 3）出现固体粪便失禁，4.1%（n = 2）出现三种情况均有失禁。21%（n = 10）抱怨其身体和社交活动受到干扰。FI与IBD类型之间无关联。FI与年龄（P = 0.005）和性别（P < 0.001）之间存在显著关联。FI对我们队列患者的QOL有显著影响。
在我们的研究中，近四分之一的患者报告有FI。FI与QOL之间存在显著相关性。因此，询问IBD患者的FI情况可发现这种使人衰弱的状况。这将有助于对该组患者尽早转诊进行失禁护理。
