Rice Teresa C, Quezada Yarini, Rafferty Janice F, Paquette Ian M
1 Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 2 Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, Ohio 3 Christ Hospital Center for Pelvic Floor Disorders, Cincinnati, Ohio.
Dis Colon Rectum. 2016 Oct;59(10):962-7. doi: 10.1097/DCR.0000000000000668.
Sacral neuromodulation using a 2-staged approach is an established therapy for fecal incontinence. Office-based percutaneous nerve evaluation is a less-invasive alternative to the stage 1 procedure but is seldom used in the evaluation of patients with fecal incontinence.
The aim of this study was to determine the clinical success of percutaneous nerve evaluation versus a staged approach.
This was a retrospective review of a prospectively maintained, single-institution database of patients treated with sacral neuromodulation for fecal incontinence.
This study was conducted at a single academic medical center.
Eighty-six consecutive patients were treated with sacral neuromodulation for fecal incontinence.
Percutaneous nerve evaluation was compared with a staged approach.
The primary outcome measured was the proportion of patients progressing to complete implantation based on >50% improvement in Wexner score during the testing phase.
Percutaneous nerve evaluation was performed in 45 patients, whereas 41 underwent a staged approach. The mean baseline Wexner score did not differ between testing groups. Success was similar between the staged approach and percutaneous nerve evaluation (90.2% versus 82.2%; p = 0.36). The mean 3-month Wexner score was not significantly different between testing methods (4.4 versus 4.1; p = 0.74). However, infection was more likely to occur after the staged approach (10.5% versus 0.0%; p < 0.05).
This study was limited by its retrospective nature and potential for selection bias.
Percutaneous nerve evaluation offers a viable alternative to a staged approach in the evaluation of patients for sacral neuromodulation in the setting of fecal incontinence. Not only are success rates similar, but percutaneous nerve evaluation also has the benefit of limiting patients to 1 operating room visit and has lower rates of infection as compared with the traditional staged approach for sacral neuromodulation.
采用两阶段方法的骶神经调节术是治疗大便失禁的一种既定疗法。门诊经皮神经评估是第一阶段手术的一种侵入性较小的替代方法,但很少用于大便失禁患者的评估。
本研究的目的是确定经皮神经评估与两阶段方法的临床成功率。
这是一项对前瞻性维护的、单机构骶神经调节术治疗大便失禁患者数据库的回顾性研究。
本研究在一个学术医疗中心进行。
86例连续的大便失禁患者接受了骶神经调节术治疗。
将经皮神经评估与两阶段方法进行比较。
主要观察指标是在测试阶段基于韦克斯纳评分改善>50%而进展至完全植入的患者比例。
45例患者接受了经皮神经评估,而41例采用了两阶段方法。测试组之间的平均基线韦克斯纳评分无差异。两阶段方法和经皮神经评估的成功率相似(90.2%对82.2%;p = 0.36)。测试方法之间的平均3个月韦克斯纳评分无显著差异(4.4对4.1;p = 0.74)。然而,两阶段方法后感染更易发生(10.5%对0.0%;p < 0.05)。
本研究受其回顾性性质和选择偏倚可能性的限制。
在大便失禁情况下对患者进行骶神经调节术评估时,经皮神经评估为两阶段方法提供了一种可行的替代方案。不仅成功率相似,而且经皮神经评估还有利于将患者限制在1次手术室就诊,并且与传统的骶神经调节术两阶段方法相比感染率更低。