神经元细胞中EWS物种的糖基化化学计量。
The glycosylation stoichiometry of EWS species in neuronal cells.
作者信息
Kamemura Kazuo, Abe Hiromi
机构信息
a Department of Bioscience , Nagahama Institute of Bio-Science and Technology , Nagahama , Japan.
出版信息
Biosci Biotechnol Biochem. 2017 Jan;81(1):165-167. doi: 10.1080/09168451.2016.1230004. Epub 2016 Sep 8.
Although Ewing sarcoma protein (EWS) is known to be glycosylated by O-linked β-N-acetylglucosamine (O-GlcNAc), the dynamics and stoichiometry of its glycosylation remain obscure. Here, we report a dynamic change in the glycosylation stoichiometry of EWS species during neuronal differentiation of embryonic carcinoma P19 cells. Our findings suggest that O-GlcNAc glycosylation participates in the regulation of EWS functions in neuronal cells.
尽管已知尤因肉瘤蛋白（EWS）可被O-连接的β-N-乙酰葡糖胺（O-GlcNAc）糖基化，但其糖基化的动力学和化学计量仍不清楚。在此，我们报道了在胚胎癌P19细胞的神经元分化过程中EWS物种糖基化化学计量的动态变化。我们的研究结果表明，O-GlcNAc糖基化参与了神经元细胞中EWS功能的调节。
Zotero 插件