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脊髓梗死是股骨骨折双侧髓内钉固定后脂肪栓塞综合征的一种罕见并发症。

Spinal cord infarction as a rare complication of fat embolism syndrome following bilateral intramedullary nailing of femur fractures.

作者信息

Kearsley RoseMarie, Galbraith John, Dalton David, Motherway Catherine

机构信息

Department of Anaesthesia and Intensive Care Medicine, University Hospital Limerick, Limerick, Ireland.

University Hospital Limerick, Limerick, Ireland.

出版信息

BMJ Case Rep. 2016 Sep 13;2016:bcr2016215690. doi: 10.1136/bcr-2016-215690.

Abstract

Fat embolism syndrome (FES) is a rare and potentially fatal complication occurring most often after long bone or pelvic fractures and orthopaedic procedures. It can consist of pulmonary, central nervous system and cutaneous manifestations. The exact pathophysiology of emboli reaching the arterial circulation is poorly understood.1 It is suggested that this may occur by either 'paradoxical' embolism or microembolism.2 3 Its true incidence is unknown but increases in the presence of multiple closed fractures. It can be a diagnostic dilemma for clinicians and if suspected diffusion-weighted MRI is the modality of choice for the investigation of the central nervous system.4 We present the case of a 22-year-old man who developed multifocal cerebral infarcts, a right-sided cerebellar infarct and an infarct in the anterior cord bilaterally at the level of C5-C6 as a result of FES.

摘要

脂肪栓塞综合征(FES)是一种罕见且可能致命的并发症,最常发生于长骨或骨盆骨折以及骨科手术后。它可表现为肺部、中枢神经系统和皮肤症状。栓子进入动脉循环的确切病理生理学机制尚不清楚。有人认为这可能通过“反常”栓塞或微栓塞发生。其真实发病率未知,但在多处闭合性骨折时会增加。对于临床医生来说,这可能是一个诊断难题,如果怀疑有脂肪栓塞综合征,弥散加权磁共振成像(MRI)是检查中枢神经系统的首选方式。我们报告一例22岁男性患者,因脂肪栓塞综合征出现多灶性脑梗死、右侧小脑梗死以及双侧C5 - C6水平脊髓前索梗死。

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本文引用的文献

2
Images in clinical medicine. Cerebral fat embolism.临床医学影像。脑脂肪栓塞。
N Engl J Med. 2012 Sep 13;367(11):1045. doi: 10.1056/NEJMicm1100944.
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Fat embolism.脂肪栓塞
Anaesthesia. 2001 Feb;56(2):145-54. doi: 10.1046/j.1365-2044.2001.01724.x.
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Fat embolism syndrome.脂肪栓塞综合征
Orthopedics. 1996 Jan;19(1):41-8; discussion 48-9. doi: 10.3928/0147-7447-19960101-09.
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Assessment of cerebral fat embolism by magnetic resonance imaging in the acute stage.
J Trauma. 1996 Mar;40(3):437-40. doi: 10.1097/00005373-199603000-00019.

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