Cohn L H, Peigh P S, Sell J, DiSesa V J
Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts 02115.
Ann Thorac Surg. 1989 Jul;48(1):69-71. doi: 10.1016/0003-4975(89)90180-x.
Ten patients underwent mitral valve re-replacement for the third to sixth time through a right thoracotomy using one-lung anesthesia, femorofemoral bypass, profound systemic hypothermia, and low-flow perfusion without aortic cross-clamping or cardioplegia. The indications for this approach were previous mediastinitis, severe right ventricular hypertension with multiple previous sternotomies, intact coronary artery bypass graft, or previous aortic valve replacement. There was 1 operative death, which was due to end-stage pulmonary hypertension and intractable right heart failure. Blood loss was minimal, and there was no major postoperative morbidity in the 9 surviving patients except for supraventricular arrhythmias.
10例患者通过右胸切口,采用单肺麻醉、股-股体外循环、深度全身低温和低流量灌注,在不阻断主动脉或不使用心脏停搏液的情况下,接受了第三次至第六次二尖瓣再次置换术。采用这种方法的适应证包括既往纵隔炎、多次开胸术后严重右心室高压、冠状动脉旁路移植完整或既往主动脉瓣置换。有1例手术死亡,原因是终末期肺动脉高压和顽固性右心衰竭。失血极少,9例存活患者除室上性心律失常外无严重术后并发症。