Wick M, Gross C C, Isenmann S, Strik H
Institut für Laboratoriumsmedizin, Klinikum der LMU München, München, Deutschland.
Liquor- und Labordiagnostik Neurologie, Department für Neurologie, Universitätsklinikum Münster, Münster, Deutschland.
Nervenarzt. 2016 Dec;87(12):1276-1281. doi: 10.1007/s00115-016-0219-5.
Cytology is an integral part of cerebrospinal fluid (CSF) analysis. It is relevant for the diagnostics and differential diagnosis of inflammatory, hemorrhagic and neoplastic central nervous system (CNS) processes. This article summarizes the recommended procedures and typical clinical patterns. In addition, modern immunocytochemical and flow cytometry methods for CSF cytology are presented. In particular, the diagnostic contribution and clinical relevance in several CNS conditions are discussed.
细胞学是脑脊液(CSF)分析不可或缺的一部分。它对于炎症性、出血性和肿瘤性中枢神经系统(CNS)疾病的诊断及鉴别诊断具有重要意义。本文总结了推荐的操作流程和典型临床模式。此外,还介绍了用于脑脊液细胞学检查的现代免疫细胞化学和流式细胞术方法。特别讨论了在几种中枢神经系统疾病中的诊断作用及临床相关性。