Theodosopoulos Philip V, Cebula Helene, Kurbanov Almaz, Cabero Arnau Benet, Osorio Joseph A, Zimmer Lee A, Froelich Sebastien C, Keller Jeffrey T
Department of Neurological Surgery, University of California San Francisco, San Francisco, California, USA.
Department of Neurosurgery, Lariboisiere University Hospital, Paris, France.
World Neurosurg. 2016 Dec;96:417-422. doi: 10.1016/j.wneu.2016.09.046. Epub 2016 Sep 19.
The zenith of surgical interest in the cavernous sinus peaked in the 1980s, as evidenced by reports of 10 surgical triangles that could access the contents of the lateral sellar compartment (LSC). However, these transcranial approaches later became marginalized, first by radiosurgery's popularity and lower morbidity, and then by clinical potential of endoscopic corridors noted in several qualitative studies. Our anatomic study, taking a contemporary look at the medial extra-sellar corridor, gives a detailed qualitative-quantitative analysis for its use with increasingly popular endoscopic endonasal approaches to the cavernous sinus.
In 20 cadaveric specimens, we re-examined the anatomic landmarks of the medial corridor into the LSC with qualitative descriptions and measurements. An illustrative case highlights a recurrent symptomatic pituitary adenoma that invaded the cavernous sinus approached through the medial corridor.
The corridor's shape varied from tetrahedron to hexahedron. Comparing right and left sides, width averaged 3.6 ± 4.5 mm and 4.0 ± 4.4 mm, and height averaged 2.3 mm and 2.1 mm, respectively. About 35% of sides showed ample space for access into the cavernous sinus. Our case report of successful outcome lends support for the safety and efficacy of this endoscopic approach.
Our re-examination of this particular surgical access into the LSC refines the understanding of the medial extra-sellar corridor as a main endoscopic access route to this compartment. Achieving safe access to the contents of the LSC, this 11th triangle is clinically relevant and potentially superior for select lesions in this region.
20世纪80年代,海绵窦手术关注度达到顶峰,有报道称存在10个可进入鞍旁外侧间隙(LSC)内容物的手术三角区。然而,这些经颅入路后来逐渐被边缘化,首先是因为放射外科的普及和较低的发病率,然后是因为一些定性研究中提到的内镜通道的临床潜力。我们的解剖学研究对鞍旁内侧通道进行了当代审视,对其在日益流行的内镜经鼻入路海绵窦手术中的应用进行了详细的定性和定量分析。
在20具尸体标本中,我们通过定性描述和测量重新审视了进入LSC的内侧通道的解剖标志。一个典型病例突出显示了一例通过内侧通道入路的复发性有症状垂体腺瘤侵犯海绵窦的情况。
通道形状从四面体到六面体不等。左右两侧比较,宽度平均分别为3.6±4.5毫米和4.0±4.4毫米,高度平均分别为2.3毫米和2.1毫米。约35%的侧面显示有足够的空间进入海绵窦。我们成功治疗的病例报告支持了这种内镜入路的安全性和有效性。
我们对这种进入LSC的特定手术入路的重新审视,完善了对鞍旁内侧通道作为进入该间隙的主要内镜入路的理解。作为第11个三角区,该入路能安全进入LSC内容物,对该区域的特定病变具有临床相关性且可能更具优势。