Paans Nadine P G, Bot Mariska, Gibson-Smith Deborah, Van der Does Willem, Spinhoven Philip, Brouwer Ingeborg, Visser Marjolein, Penninx Brenda W J H
Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
J Psychosom Res. 2016 Oct;89:26-31. doi: 10.1016/j.jpsychores.2016.07.013. Epub 2016 Jul 22.
A range of biological, social and psychological factors, including depression and anxiety disorders, is thought to be associated with higher body mass index (BMI). Depression and anxiety disorders are associated with specific psychological vulnerabilities, like personality traits and cognitive reactivity, that may also be associated with BMI. The relationship between those psychological vulnerabilities and BMI is possibly different in people with and without depression and anxiety disorders. Therefore, we examined the relationship between personality traits, cognitive reactivity and severity of affective symptoms with BMI in people with and without depression and anxiety disorders.
Data from 1249 patients with current major depressive and/or anxiety disorder and 631 healthy controls were sourced from the Netherlands Study of Depression and Anxiety. Linear and logistic regression analyses were used to determine the associations between personality traits (neuroticism, extraversion, conscientiousness), cognitive reactivity (hopelessness, aggression, rumination, anxiety sensitivity), depression and anxiety symptoms with BMI classes (normal: 18.5-24.9, overweight: 25-29.9, and obese: ≥30kg/m(2)) and continuous BMI. Due to significant statistical interaction, analyses were stratified for healthy individuals and depressed/anxious patients.
Personality traits were not consistently related to BMI. In patients, higher hopelessness and aggression reactivity and higher depression and anxiety symptoms were associated with higher BMI. In contrast, in healthy individuals lower scores on hopelessness, rumination, aggression reactivity and anxiety sensitivity were associated with higher BMI.
These results suggest that, particularly in people with psychopathology, cognitive reactivity may contribute to obesity.
一系列生物、社会和心理因素,包括抑郁症和焦虑症,被认为与较高的体重指数(BMI)相关。抑郁症和焦虑症与特定的心理易感性有关,如人格特质和认知反应性,这些也可能与BMI相关。这些心理易感性与BMI之间的关系在患有和未患有抑郁症和焦虑症的人群中可能有所不同。因此,我们研究了患有和未患有抑郁症和焦虑症的人群中人格特质、认知反应性和情感症状严重程度与BMI之间的关系。
来自1249名当前患有重度抑郁和/或焦虑症的患者以及631名健康对照的数据源自荷兰抑郁症和焦虑症研究。线性和逻辑回归分析用于确定人格特质(神经质、外向性、尽责性)、认知反应性(绝望感、攻击性、沉思、焦虑敏感性)、抑郁和焦虑症状与BMI类别(正常:18.5 - 24.9、超重:25 - 29.9、肥胖:≥30kg/m²)以及连续BMI之间的关联。由于存在显著的统计交互作用,分析针对健康个体和抑郁/焦虑患者进行了分层。
人格特质与BMI并非始终相关。在患者中,较高的绝望感和攻击性反应性以及较高的抑郁和焦虑症状与较高的BMI相关。相比之下,在健康个体中,较低的绝望感、沉思、攻击性反应性和焦虑敏感性得分与较高的BMI相关。
这些结果表明,特别是在患有精神病理学疾病的人群中,认知反应性可能导致肥胖。