Suppr超能文献

腹主动脉瘤破裂患者中已知腹主动脉瘤的比例较高,这表明监测存在不足。

High proportion of known abdominal aortic aneurysm in patients with rupture indicates surveillance deficiency.

作者信息

Zommorodi Sayid, Roy Joy, Steuer Johnny, Hultgren Rebecka

机构信息

Department of Surgery, Section for Vascular Surgery, Södersjukhuset, Stockholm, Sweden; Department of Clinical Science and Education, Karolinska Institutet, Stockholm, Sweden.

Department of Vascular Surgery, Karolinska University Hospital, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

出版信息

J Vasc Surg. 2016 Oct;64(4):949-955.e1. doi: 10.1016/j.jvs.2016.04.007.

Abstract

OBJECTIVE

This study assessed the proportion of previously known abdominal aortic aneurysm (AAA) in patients presenting with a ruptured AAA (rAAA) and analyzed the reasons for nontreatment at the time of the initial AAA diagnosis.

METHODS

This retrospective, observational study included all patients with rAAA admitted to a hospital in the counties of Stockholm and Gotland during 2009 to 2013. The patients' records were retrospectively reviewed, with extraction of data on previously detected AAA, demographics, and mortality at 30 and 90 days.

RESULTS

We identified 283 patients (76% men) with a mean age of 78.7 years. An AAA had been previously detected in 85 (30%). The overall mortality was higher (68% vs 53%; P = .018) and the intervention rate was lower in patients with a previously detected AAA (59% vs 82%, P < .001). The 90-day mortality rate for all treated rAAA was 43%. Reasons for nontreatment at the initial AAA detection were denial of elective surgery in 31 (36%), patient choice in 15 (18%), size-related in 11 (13%), and surveillance deficiency in 26 (31%). The latter group included patients who failed to comply, missed referral for computed tomography scans, and lack of follow-up of radiology reports. At the time of rupture, 22 patients (85%) were treated, with 30-day and 90-day mortality rates both at 41% (n = 9).

CONCLUSIONS

One-third of patients admitted with a rAAA had a previously detected AAA. The surgeons' decision to deny elective surgery and surveillance deficiency were the two main reasons for nontreatment at time of the AAA diagnosis. Improved patient-specific protocols to reduce the surveillance gaps and new methods of determining rupture risk in each case of AAA could be two possible future strategies to reduce the incidence of rupture.

摘要

目的

本研究评估了腹主动脉瘤破裂(rAAA)患者中既往已知腹主动脉瘤(AAA)的比例,并分析了初次诊断AAA时未接受治疗的原因。

方法

这项回顾性观察性研究纳入了2009年至2013年期间在斯德哥尔摩和哥特兰岛各县医院收治的所有rAAA患者。对患者的记录进行回顾性审查,提取有关既往检测到的AAA、人口统计学数据以及30天和90天死亡率的数据。

结果

我们确定了283例患者(76%为男性),平均年龄为78.7岁。此前已检测到AAA的患者有85例(30%)。既往检测到AAA的患者总体死亡率更高(68%对53%;P = 0.018),干预率更低(59%对82%,P < 0.001)。所有接受治疗的rAAA患者的90天死亡率为43%。初次检测到AAA时未接受治疗的原因包括31例(36%)拒绝择期手术、15例(18%)患者自主选择、11例(13%)与大小有关以及26例(31%)监测不足。后一组包括未遵守规定、错过计算机断层扫描转诊以及缺乏放射学报告随访的患者。在破裂时,22例患者(85%)接受了治疗,30天和90天死亡率均为41%(n = 9)。

结论

三分之一因rAAA入院的患者此前已检测到AAA。外科医生拒绝择期手术的决定和监测不足是AAA诊断时未接受治疗的两个主要原因。改进针对患者的方案以减少监测差距以及确定每例AAA破裂风险的新方法可能是未来降低破裂发生率的两种策略。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验