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下肢闭塞性血管疾病患者的甲状旁腺功能及其纠正的可能性。

Parathyroid gland function and the possibility of its correction in patients with obliterative vascular disease of the lower limbs.

作者信息

Zoloev G K, Slepushkin V D, Sokolovich G E, Poyarkov V D, Argintaev E S, Smirnov A V

机构信息

Research Institute of Cardiology, Tomsk Scientific Centre, Academy of Medical Sciences, USSR.

出版信息

Cor Vasa. 1989;31(3):203-9.

PMID:2766752
Abstract

Parathyroid gland function and the possibility of its correction were studied in 43 patients with obliterative vascular disease of the lower limbs, and in 24 healthy, mostly male, controls. Parathormone (PTH) concentrations in blood plasma samples were determined by radioimmunoassay. Patients with obliterative vascular diseases of the lower limbs were found to have increased activity of parathyroid gland. The role played by hyperparathyroidism in the pathogenesis of obliterative vascular diseases of the lower limbs as well as the possibility of its correction by betablocker and encephalin analogue administration is discussed.

摘要

对43例下肢闭塞性血管疾病患者以及24名健康对照者(大多数为男性)的甲状旁腺功能及其纠正的可能性进行了研究。通过放射免疫分析法测定血浆样本中的甲状旁腺激素(PTH)浓度。发现下肢闭塞性血管疾病患者的甲状旁腺活性增加。讨论了甲状旁腺功能亢进在下肢闭塞性血管疾病发病机制中的作用以及通过给予β受体阻滞剂和脑啡肽类似物进行纠正的可能性。

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