Zhao Yingke, Liu Yue, Chen Keji
Cardiovascular Diseases Centre, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China; School of Chinese Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
Cardiovascular Diseases Centre, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Oxid Med Cell Longev. 2016;2016:2124638. doi: 10.1155/2016/2124638. Epub 2016 Sep 7.
Tetramethylpyrazine, a natural compound from (), has been extensively used in China for cardiovascular and cerebrovascular diseases for about 40 years. Because of its effectiveness in multisystems, especially in cardiovascular, its pharmacological action, clinical application, and the structural modification have attracted broad attention. In this paper its mechanisms of action, the clinical status, and synthetic derivatives will be reviewed briefly.
川芎嗪是一种从()中提取的天然化合物,在中国用于治疗心脑血管疾病已有约40年历史。由于其在多系统尤其是心血管系统中的有效性,其药理作用、临床应用及结构修饰已引起广泛关注。本文将对其作用机制、临床现状及合成衍生物作简要综述。