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参加代谢性结石预防共享医疗预约的患者结石风险因素降低。

Patients Attending Shared Medical Appointments for Metabolic Stone Prevention Have Decreased Stone Risk Factors.

作者信息

Jhagroo R Allan, Nakada Stephen Y, Penniston Kristina L

机构信息

1 Department of Medicine, University of Wisconsin School of Medicine and Public Health , Madison, Wisconsin.

2 Department of Urology, University of Wisconsin School of Medicine and Public Health , Madison, Wisconsin.

出版信息

J Endourol. 2016 Nov;30(11):1262-1268. doi: 10.1089/end.2016.0500. Epub 2016 Oct 27.

Abstract

INTRODUCTION

Shared medical appointments (SMAs) have decreased patients' wait time to initial stone clinic appointment, standardized education, and increased exposure to nutrition therapy. We assessed the effectiveness of SMAs in reducing patients' urinary stone risk factors.

MATERIALS AND METHODS

Patients who established care in our stone clinic in an SMA between March 2012 and August 2015 were sequentially identified. After eliminating those without follow-up urine collections or whose urinary creatinine excretion between the two collections varied by >40%, 113 patients were included (M:F 63:50; 54 ± 15 years; body mass index [BMI] 30.6 ± 6.7). Results from before and after the SMA were compared with those from a similar cohort of patients who attended individual patient appointments (IPAs) for their first stone clinic visit (n = 63; M:F 37:26; 54 ± 14 years; BMI 30.1 ± 8.2). All patients received individualized medical therapy for stone prevention.

RESULTS

After medical and nutritional therapy, SMA patients with elevated risk(s) at baseline achieved significant reductions in uric acid, calcium, and sodium; p ≤ 0.001 for all. Those with low urine magnesium, low urine volume, low urine pH, and/or low urine citrate at baseline achieved increases; p ≤ 0.0008 for all. IPA patients with elevated baseline risk factors achieved reductions in oxalate and uric acid (p ≤ 0.004 for both) but neither calcium nor sodium and an increase in citrate (p = 0.003) but not magnesium.

CONCLUSIONS

Patients from SMAs reduced their stone recurrence risk and compared favorably with patients from IPAs. Contributing factors may include shorter time from stone event to appointment and more standardized education for patients attending SMAs.

摘要

引言

共享医疗预约(SMA)减少了患者初次就诊结石门诊的等待时间,实现了教育标准化,并增加了营养治疗的机会。我们评估了SMA在降低患者尿路结石风险因素方面的有效性。

材料与方法

依次确定2012年3月至2015年8月期间在我们结石门诊通过SMA建立治疗关系的患者。在排除那些没有后续尿液收集或两次收集之间尿肌酐排泄量变化超过40%的患者后,纳入113例患者(男:女为63:50;年龄54±15岁;体重指数[BMI]30.6±6.7)。将SMA前后的结果与一组类似的首次就诊结石门诊时接受个体患者预约(IPA)的患者结果进行比较(n = 63;男:女为37:26;年龄54±14岁;BMI 30.1±8.2)。所有患者均接受了个体化的结石预防药物治疗。

结果

经过药物和营养治疗后,基线时风险升高的SMA患者尿酸、钙和钠显著降低;所有指标p≤0.001。基线时尿镁低、尿量低、尿pH值低和/或尿柠檬酸盐低的患者这些指标有所升高;所有指标p≤0.0008。基线风险因素升高的IPA患者草酸盐和尿酸降低(两者p≤0.004),但钙和钠未降低,柠檬酸盐升高(p = 0.003),但镁未升高。

结论

SMA患者降低了结石复发风险,与IPA患者相比具有优势。促成因素可能包括从结石发病到就诊的时间较短,以及参加SMA的患者接受了更标准化的教育。

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